Sentences with phrase «niche cells»

The blood stem cells are located in specialized niches in the bone marrow and are surrounded by specialized niche cells.

Looking further into the intestinal crypts of both the transgenic and wild - type mice, the research team made what they consider a surprising finding: Not only was HMGA1 causing the stem cells themselves to self - renew or proliferate more rapidly in the transgenic animals, but it was also increasing the number of Paneth cells, a type of niche cell known to support intestinal stem cells.

However, it is still unclear what type of niche cells make the Wnts and R - spondins.

Techniques enabling the isolation of specific cell populations have advanced our ability to identify and characterize niche cell types which may be used to replace or engineer cells / tissue.

In contrast, forced expression of upd within niche cells delayed the loss of germline stem cells in older males.

If these niche cells can not make Wnts, mice do not develop adult intestines, and if these niche cells can not make RSPO3, mice can not repair the intestine after injury.

The oncologists in Bern were able to show that messenger substances secreted by the T killer cells modulate the niche cells.

In turn, the niche cells control the production and also the differentiation of the blood stem cells.

When these stem cells were removed from the mice and grown in a culture dish without their niche cells, they gave rise to «mini-intestines» much more readily than intestinal stem cells from mice on a normal diet.