Sentences with phrase «niche cells make»
Not exact matches
Looking further into the intestinal crypts of both the transgenic and wild - type mice, the research team made what they consider a surprising finding: Not only was HMGA1 causing the stem cells themselves to self - renew or proliferate more rapidly in the transgenic animals, but it was also increasing the number of Paneth cells, a type of niche cell known to support intestinal stem cells.
https://www.sciencedaily.com/
If these niche cells can not make Wnts, mice do not develop adult intestines, and if these niche cells can not make RSPO3, mice can not repair the intestine after injury.
Stem cells are encapsulated into niches made from materials designed to mimic the natural extracellular matrix.
In an earlier study, Jones had shown that the hub cells secrete the self - renewal factor upd, which signals neighboring stem cells to maintain stem cell fate, making hub cells an essential component of the stem cell niche.