Sentences with word «nicotinic»
The word "nicotinic" refers to anything that is related to nicotine, a chemical compound found in tobacco. Full definition
Precisely where these findings will lead drug treatment strategies is unclear, but this work provides insight into the role of nicotinic receptors in the vulnerability to multiple classes of addictive drugs.»
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Previous research had shown that nicotine seems to have conflicting effects on different types of nicotinic acetylcholine receptors, proteins on the surface of brain cells that respond to nicotine and the naturally occurring neurotransmitter acetylcholine.
An additional role for nicotinic acid adenine dinucleotide phosphate (NAADP) has been suggested but never confirmed.
And, wheat germ is rich in vitamins E, B1, B2 and B6, as well as nicotinic acid.
Neonicotinoids target nicotinic acetylcholine receptors (nAChRs) in the insect central nervous system.
Niacin, also called Nicotinic Acid is one of the B vitamins and the subject of the Coronary Drug Project (CDP) which was published in the Journal of the American College of Cardiology in 1986.
b) Mice bred to lack the β2 subunit of nicotinic cholinergic receptors have a reduced reward response to cocaine.
Here we summarize the results of a five year collaboration involving three research groups pursuing the development of novel antidepressant drugs targeting α4β2 nicotinic acetylcholine receptors (nAChR).
When you roast the beans, this other alkaloid turns into nicotinic acid, also known as niacin.
Anand, who studies the association between nicotinic receptors and central nervous system disorders, was inspired to pursue a model of human neural biology after encountering disappointing results in a rodent study of an experimental autism drug.
This illustration shows how the rabies virus inhibits nicotinic receptors in the brain, which interferes with communication and induces frenzied behavior.
Spinosad works by activating nicotinic acetylcholine receptors in the flea nervous system causing an overload of the flea nervous system.
To maintain sirtuin function therefore it is necessary to replenish NAD + levels through nicotinic acid or nicotamide biosynthesis pathways.
He uses various electrophysiological and voltage - sensitive dye recording techniques to study hippocampal excitability and circuits regulated by nicotinic receptor activation to gain insights into disease mechanisms.
A better understanding of such receptors, he says, may help researchers more efficiently target nicotinelike drugs in patients with diseases that may involve nicotinic receptors, including Parkinson's disease, Tourette's syndrome, and schizophrenia.
Lindstrom and his colleagues inserted genes for human nicotinic receptors into frog eggs and incubated them with levels of nicotine similar to those found in the blood of a human smoker.
These chemicals work as agonists of insect nicotinic acetylcholine receptors, but their effect on mammals has been unclear.
The nervous system is studded with nicotinic receptors, neurons that help regulate the release of important neurotransmitterssuch as acetylcholine, serotonin, and dopamine.
A Gain - of - Function Mutation in the α9 Nicotinic Acetylcholine Receptor Alters Medial Olivocochlear Efferent Short - Term Synaptic Plasticity
Abstract Pentameric channel - receptors, including nicotinic acetylcholine, glycine and GABAA receptors, play a key role in fast excitatory and inhibitory transmission in the nervous system and are the target of numerous therapeutic and addictive drugs.
Other functionally distinct compounds are classified as nicotinic anthelmintics, glutamate-gated chloride channel potentiators or macrolides.
The structure of a eukaryotic nicotinic acid phosphoribosyltransferase reveals structural heterogeneity among type II PRTases.
Antidepressant - like Activity of AMOP - H - OH («SAZETIDINE - A») in the Forced Swim TSest is Mediated by High Affinity Nicotinic Acetylcholine Receptors.
It turns out when you burn nicotine, you get nicotinic acid, also known as niacin.
Multivitamins contain about 25 to 50 milligrams of niacinamide (or sometimes nicotinic acid); B - complex supplements contain 50 to 100 milligrams of niacinamide; and a single niacin supplement usually contains 500 milligrams.
To lower cholesterol I would suggest taking pure nicotinic acid staring from lower doses of 2 times 50 to 100 mg after meals and slowly increasing the dose while controlling symptoms.
More specifically, imidacloprid blocks nicotinic acetylcholine receptors.
The CHRNA5 - CHRNA3 - CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African — Americans and in European — Americans
The researchers report that mecamylamine reduces the release of dopamine by blocking binding sites on so - called nicotinic cholinergic synapses.