Sentences with phrase «nigra pars»
Dopamine (DA) neurons are found in the ventral tegmental area (VTA) and the substantia nigra pars compacta (SNc).
https://elifesciences.org/
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of dopamine - producing neurons in the substantia nigra pars compacta (SNpc) and an accumulation of α - synuclein (α - syn) protein.
Parkinson's disease (PD) is a progressive neurodegenerative disorder that is characterized by the loss of dopamine neurons in the substantia nigra pars compacta, culminating in severe motor symptoms,
Several mouse models of DJ - 1 deficiency have been developed, but they do not have dopaminergic neuron cell death in the substantia nigra pars compacta (SNpc).
These symptoms are the result of the loss of specialized cells in an area of the brain called the substantia nigra pars compacta (SNc) that specialize in producing the chemical signal - molecule dopamine and are responsible for turning off excess firing of neurons that control muscles.
This group of symptoms is caused by the progressive loss of a group of neurons in an area of the brain called the substantia nigra pars compacta (SNc).
We also observe a significant loss of dopaminergic neurons in the substantia nigra pars compacta 60 days after infection.
When a rewarding choice has been made, the substantia nigra pars compacta (SNc) releases dopamine into the striatum to reinforce connections between cortex and striatum, so that rewarded actions are more likely to be repeated.
Not exact matches
''... it could be hypothesized that PD is, at least in part, a type of «segmental» aging, in which specific, localized, and accelerated aging mechanisms, which for reasons at present largely unknown, markedly affect dopaminergic (DA) neurons in the pars compacta region of the midbrain substantia nigra (SnPC).»