Sentences with phrase «nigrostriatal degeneration»
«One possible explanation is that UPDRS reflects primarily deficits arising from nigrostriatal degeneration, whereas CSF α - synuclein levels are influenced by the whole brain and may serve as a proxy for total brain pathology,» says Dr. Zhang.
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The Toll - Like Receptor - 3 Agonist Polyinosinic: Polycytidylic Acid Triggers Nigrostriatal Dopaminergic Degeneration
In terms of pathogenic mechanisms of PD, given that miR - 181a is selectively up - regulated in nigrostriatal DA neurons of the PD brain [13], our current findings suggest that this up - regulation in miR - 181a may contribute to the ongoing mDA axonal degeneration by inhibiting BMP - Smad signalling in vivo.