Moussa is an inventor on a Georgetown University patent application for use of
nilotinib for the treatment of neurodegenerative disease.
Moussa conducted the preclinical research that led to the discovery of
nilotinib for the treatment of neuro - degenerative diseases, then partnered with Pagan for the clinical study.
Moussa and other Georgetown researchers are planning larger clinical trials with
nilotinib for patients with Parkinson's and other similar diseases including Alzheimer's disease, likely to begin this year.
Also, Georgetown holds an issued US patent on related technology for the use of
nilotinib for the treatment of certain neurodegenerative diseases and has other pending patent applications in US and foreign jurisdictions.
GUMC says its researchers are now planning larger clinical trials with
nilotinib for patients with Parkinson's and other similar diseases including Alzheimer's disease, likely to begin in 2016.
Not exact matches
(Moussa is listed as an inventor on a patent application that Georgetown University filed related to
nilotinib and the use of other tyrosine kinase inhibitors
for the treatment of neurodegenerative diseases.)
In the proof of concept study, 12 patients received
nilotinib, an FDA - approved drug
for leukemia.
Druker said that Gleevec's long - term efficacy also offers a benchmark
for comparative testing of two other similar kinase inhibitors, dasatinib and
nilotinib, now underway.
In a significant, yet unusual judgment the Court of Justice of the European Union (CJEU) upheld the General Court's decision (T - 140 / 12; Teva Pharma v. EMA) that had affirmed the European Medicines Agency's (EMA) rejection of Teva's generic drug application
for Glivec ® (active substance - imatinib), not due to the reference product's own orphan drug exclusivity but in view of orphan drug exclusivity of a similar medicinal product — Tasigna ® (active substance -
nilotinib).
However, the General Court upheld the EMA's decision refusing Teva's generic application
for imatinib in view of
nilotinib's orphan drug exclusivity pertaining to CML.