Differential inducible
nitric oxide synthase expression in systemic and pulmonary vessels after endotoxin.
In wild - type mouse blood vessels, estrogen attenuates vasoconstriction by an ERβ - mediated increase in inducible
nitric oxide synthase expression.
Not exact matches
In diabetic rat models, female mesenteric arteries show greater abnormal vascular responses demonstrated by greater impairment of acetycholin - induced relaxation and an increased
expression of endothelial
nitric oxide synthase.
Their antioxidant and anti-inflammatory activities are largely due to their abilities to scavenge the reactive oxygen species (ROS) and improvement of antioxidant status by attenuating the activity of NF - κB and suppressing the
expression of several inflammatory cytokines and chemokines including monocyte chemotactic protein - 1 (MCP - 1),
nitric oxide synthase, cyclooxygenases, lipoxygenases, cellular adhesion molecules, tumor necrosis factor and interleukins.
(8) In another study, the anti-inflammatory properties of the active ingredient in schisandra, schisandrin, were shown to result from the inhibition of
nitric oxide (NO) production, prostaglandin E2 (PGE2) release, cyclooxygenase - 2 (COX - 2) and inducible
nitric oxide synthase (iNOS)
expression.