Sentences with phrase «non-retroelement open reading frames»

The open reading frame of the sequenced clone coded for 97 amino acids, including the known amino acid sequence of this polypeptide.

Patients with mutations in the chromosome 9 open reading frame 72 (C9ORF72) gene have all or some symptoms associated with both disorders.

Translation then switches from the defective message to a short open reading frame on tmRNA that tags the defective nascent peptide chain for degradation.

Boxes above the central black line represent open reading frames (ORFs) that are encoded on the forward strand, while boxes underneath the black line represent reverse - strand encoded ORFs.

(A) Overview of Acks cDNA and open reading frame (ORF) analysis.

Frequently insertions / deletions alter the open reading frame (ORF) of the target gene, disrupting the gene function downstream of the DSB.

Horizontal boxes under the upper yellow and black bar indicate open reading frame analysis in each reading frame of the Acks cDNA, respectively.

Open Reading Frame E3 - 10.9 K of Subspecies B1 Human Adenoviruses Encodes a Family of Late Orthologous Proteins That Vary in Their Predicted Structural Features and Subcellular Localization.

Additionally, P - eIF2α dependent translation of mRNAs regulated by upstream open reading frames (uORFs) contributes to the molecular signature of stemness.

This genome encodes intact open reading frames for all nine HIV - 1 genes.

US28 is a protein encoded by the CMV open reading frame which shows a striking homology with CCR1.

It is known that one of the pathways involved in cutaneous cancer is mediated through CDKN2A which is a gene associated with melanoma dysregulation through its pro-oncogenic products p16INK4a (Cyclin - Dependent Kinase Inhibitor P16) and p14ARF (P14 alternate open reading frame)[28].

This particular open reading frame is absent in P. simiovale and seems that have occurred subsequent to the expansion and is not likely to be implicated in the expansion itself.

We further obtained comparative and experimental evidence indicating widespread translational regulation by upstream open reading frames.

The published P. coatneyi genome assembly14 (accession numbers CP016239 to CP016252 from NCBI) contains several large open reading frames that appear to correspond to coding sequences, especially in the subtelomeric regions.

To prepare UAS overexpression constructs, the entire open reading frames of GBP1 and GBP2 were isolated by RT - PCR using cDNA made from w1118 wandering larvae with primer sets as described in S1 Table.

To test for Plasmodium falciparum DNA, PCR primers were designed that specifically amplify small subtelomeric variable open reading frame (STEVOR), apical membrane antigen 1 (AMA1), and merozoite surface protein 1 (MSP1) gene fragments with sizes of 100 to 250 base pairs (bp).

The flavivirus genome, approximately 10.5 kb in size, encodes three structural proteins [capsid (C), membrane (PrM and M) and envelope (E)-RSB- and seven non-structural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5) in one open reading frame with subsequent cleavage [9].

Open boxes indicate untranslated regions and colored boxes indicate open reading frames.

Each allele eliminated the pathogenic p.K1872X mutation and removed 59 or 22 amino acids from the predicted encoded protein, while restoring the open reading frame to encode the critical C terminal region of BRCA2 (Fig. 1C, labeled D1 and D2, Supplementary Tables S1 and S2).

We used the P - element insertion line, P -LCB- EP -RCB- G19340, whose insertion locus is 80 bp upstream of the 5 ′ - end of the open reading frame of the gbp1 gene (Fig 2E).

This deletion removes the entire gbp1 open reading frame and 594 bp of 5 ′ - end of gbp2 open reading frame.

All deletion alleles eliminated the pathogenic p.K1872X mutation and restored the open reading frame of BRCA2, producing predicted proteins of residue length 3,409 to 3,212 compared with the 3,418 amino acid full - length BRCA2 protein.

The predicted open reading frames (ORFs) for most of these transcripts are truncated, due to a premature stop codon.

After assembly, the plasmids were manually quality controlled and open reading frames (ORFs) were predicted using Glimmer 3.02 [53].

The start and stop codons tell the ribosome where to start or stop translating and this way they define an open reading frame.

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Not exact matches

The press frames every story about Francis as a break with the rigidity, dogmatism etc, of his predecessors — Benedict's back in the doghouse, so to speak — and the latest example of a new, caring, open, pastoral (read: lenient) Catholicism.

An assay developed in our lab uses a reference protein that is translated from the same open - reading frame and separated from the protein of interest by a 2A self - cleaving peptide (Goedhart et al, 2010).

developed in our lab uses a reference protein that is translated from the same open - reading frame and separated from the protein of interest by a

Relying on a combination of archival footage, the prison letters of the doomed dead men walking (as read by impersonators Tony Shahloub and John Turturro), the reflections of sympathetic lefties like Professor Howard Zinn, and the folksinging of Arlo Guthrie, the movie does a decent job of convincing any open - minded viewer that Sacco and Vanzetti were indeed framed.

This melancholy arrives in its opening frames when a young woman hangs a hotel key on a bust / memorial and begins reading from a hardback entitled «The Grand Budapest Hotel».

Recognizing key features of a persuasive speech - Higher Level Reading Skills Adaptation of opening fight scene in Romeo and Juliet Character Analysis activity sheets for Tybalt and Benvolio (Higher order reading skills - L. 5) Script writing frame for lower Reading Skills Adaptation of opening fight scene in Romeo and Juliet Character Analysis activity sheets for Tybalt and Benvolio (Higher order reading skills - L. 5) Script writing frame for lower reading skills - L. 5) Script writing frame for lower ability

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You read that correctly, once all of your changes are made and applied, it does not need to remain open as an active frame for the settings to stay.

In Great Pyrenees, English Mastiff, and bullmastiff dogs, a C73T mutation in exon 2 causes a premature translation termination that limits the open - reading frame to 25 codons, compared with 580 codons in the wild - type mRNA (cmr1) and in Coton de Tulears a G482A transition changes an evolutionarily conserved glycine residue to aspartic acid (cmr2).

Relax in wide - open, sun - filled spaces, framing courtyards and swim...... Continue reading

Taking up the reigns as Geralt, a witcher (read: monster - slayer) that gets framed for murder in the game's opening act, a quest to clear your name develops.

The streamlined bank of cabinetry — deep and wide for optimum storage space — with barely visible hardware is framed by a sleek Corian countertop and doesn't read too kitcheny in the open - concept room.