Sentences with phrase «nonfunctional protein»

Signs of ivermectin toxicosis can occur in any breed but are most common in ivermectin - sensitive breeds such as collies and other herding breeds.20, 21 Ivermectin sensitivity is derived from a frameshift deletion mutation of the multidrug resistance gene (MDR1; the most recent nomenclature is ABC ±), resulting in a severely truncated, nonfunctional protein product.

One of these cancer targets is a so - called «nonsense» protein, a nonfunctional protein that is the result of a misread DNA sequence.

Not exact matches

Psuedogenes are remnants of genes that once served a purpose in our genome that they no longer fulfil, because of mutations that have rendered the genes nonfunctional, i.e., they no longer lead to the production of proteins (long chains of amino acids) that once contributed to specific characteristics in ancient ancestors.

Chemical biologists led by Dana - Farber's Nathanael Gray, PhD, designed and custom - made a compound called THZ1 that forms a particularly strong bond with CDK7, rendering the protein essentially nonfunctional.

Bacteria stay perfectly intact too — except that they are quite dead, because the pressure contorts their DNA and proteins into nonfunctional shapes.

Unfortunately, accumulated misfolded and nonfunctional (dark) fluorescent proteins can not be ignored.