Sentences with phrase «nonhuman cells»

In fact, here is a wacky fact that might make you feel completely gross: Our bodies are inhabited by 3 to 10 times as many nonhuman cells as human cells.

Not exact matches

That breakthrough was one of a six - year chain of discoveries that included his 2007 work demonstrating the nuclear transfer method to create embryonic stem cells from a nonhuman primate.

Vaccine - mediated protection of nonhuman primates against low doses of cell - free HIV - 1, HIV - 2, or simian immunodeficiency virus (SIV) has been demonstrated.

Tests in mice and nonhuman primates had shown TGN1412 to be safe, but when it was injected into humans — in a dose less than 1/500 of what was given to monkeys — it caused a massive release of infection - fighting T cells that overstimulated the patients» immune systems, resulting in multiple organ failure.

He says more work on human cells and in nonhuman primates is needed to confirm whether this mutation is really the culprit in microcephaly.

The experiment shows that precursor cells can develop into functional organs when placed within the body of an adult mammal, says Takebe, who hopes to use the technique to grow organs in nonhuman primates and eventually in humans.

Second, the report recommends banning research that attempts to transplant enough human - derived neural cells into a nonhuman primate to prompt human - like behavior.

Scientists seeking to understand the neural mechanisms underlying social cognition and emotion have drawn on a variety of methods, including studies of patients with neurological damage and single - cell recording of brain activity in nonhuman animals.

In the paper, publishing September 26 in the ISSCR's journal Stem Cell Reports, published by Cell Press, iPSCs from nonhuman primates successfully developed into the neurons depleted by Parkinson's disease while eliciting only a minimal immune response.

The results, published in the current issue of Human Molecular Genetics, open the door for pursuing gene editing in nonhuman primates as models for new therapies, including pharmacological, gene - and stem cell - based therapies, said Keith Latham, MSU animal science professor and lead author of the study.

«The use of nonhuman oocytes for SCNT is currently the only ethically justifiable option given the large numbers of eggs required to derive cloned human stem cell lines,» he said.

Longitudinal studies in animals that spontaneously develop T2D (nonhuman primates and domestic cats) showed that detection of IAPP aggregates precedes β cell dysfunction and clinical signs of the disease (Howard, 1986; de Koning et al., 1993; Ma et al., 1998).

In an emphatic letter published today in Science, 11 researchers argue that NIH should reverse its decision against funding studies in which scientists implant human stem cells into early, nonhuman embryos.

High - fat diet consumption during pregnancy and the early post-natal period leads to decreased < i > α cell plasticity in the nonhuman primate.: High - fat diet causes decreased α cell plasticity.

Under the proposed NIH policy, taxpayer funds would be allowed for experiments in which human cells are added to early - stage embryos of all animals except nonhuman primates, such as chimpanzees and monkeys, because they are so similar to humans.

The NIH has for years supported research in which human cells are transplanted into animal models, and it continues to fund human / nonhuman chimera research that lies outside the scope of research singled out in its notice of moratorium.»

Cells increase before zoster and PD - 1 expression increases at the time of zoster in immunosuppressed nonhuman primates latently infected with simian varicella virus.

Two years ago, nonhuman primate studies conducted by Jason Brenchley's laboratory at the National Institute of Allergy and Infectious Diseases identified a previous unidentified cell in the gut that can produce interleuken - 17 — a cytokine that is concentrated in mucosal tissues and produced in response to bacterial and fungal antigens.

A CD3xCD123 bispecific DART for redirecting host T cells to myelogenous leukemia: preclinical activity and safety in nonhuman primates

Starting with Neu5Gc a sugar in nonhuman mammalian meat that incorporates into cells and brings on an autoimmune response.

Utilizing the osteocalcin promoter for restricting the replication of a canine adenovirus to dog osteosarcoma cells, we generated and tested the first nonhuman oncolytic adenovirus.