Sentences with phrase «normal adult cells»

PK comes in several forms, and many normal adult cells use PKM1, which favors the TCA cycle.

We are developing dendritic cell - based vaccines targeting telomerase, a protein expressed in over 95 percent of cancers and rarely found in normal adult cells.

In most normal adult cells, however, telomerase is switched off almost entirely to prevent the dangers of runaway cell proliferation.

Not exact matches

The Zika virus can cross the blood - brain barrier, and could target cancer cells, sparing normal adult brain tissue and opening a potential new way to attack the disease.

The estimate is that normal, healthy adults have ten times as many microbial cells as human cells within their bodies; countless more populate the environment around us.

The pluripotent stem cell - derived muscle fibers develop reservoirs of «satellite - like cells» that are necessary for normal adult muscles to repair damage, while the muscle from the previous study had much fewer of these cells.

But a clone develops from the nuclear DNA taken from a normal cell in an adult animal.

But many in the field will be waiting for the next steps: testing whether the resulting mouse pups are genetically normal, trying out the technique in other animals, and using other and less controversial types of cells — such as stem cells that can be extracted and cryopreserved from adult testicular tissue — as the starting point.

One of the expected dangers of cloning is that worn down telomeres will be inherited from the adult cells used in lieu of an egg or sperm cell, and indeed the telomeres of adult clones are often shorter than normal.

We're manipulating genes in the cell nucleus to produce specific proteins, changing the normal recipe for growth and maturation, and transforming adult cells into a new type of cell with the ability to morph into any other cell type,» said Cooke, senior author and chair of the Department of Cardiovascular Sciences.

Researchers at the Whitehead Institute in Cambridge, Massachusetts, US, have now found that adult stem cells in bone marrow gradually lose their ability to regenerate without their normal complement of membrane - bound prions.

Cardiologist Dr. Leslie Miller discusses the vital role of adult stem cells in helping the body repair itself as well as the potential benefits of cell therapy as an alternative option if you are living with symptoms of a chronic condition such as coronary artery disease or osteoarthritis that affect your ability to live a normal life.

Scientists at the Burnham Institute for Medical Research (Burnham) have discovered how HIV / AIDS disrupts the normal replication of stem cells in the adult brain, preventing new nerve cells from forming.

«Preliminary results show that BCAR4 is only active in the cancer cells and not in normal adult tissues.

Induced pluripotent stem cells that were reprogrammed from normal adult human tissue.

My post-doctoral work on the identification of genes required for normal germ line development and fertility led to the discovery that the germ line is exquisitely sensitive to mutations in components of the mitotic spindle that have the potential to lead to aneuploidy — this sensitivity may also extend to embryonic and adult stem cells.

For setting cancer in the context of ageing tissue, study of normal adult homeostasis is important — we are studying mutational processes, clonal dynamics and cellular competition in thousands of non-cancerous cells and samples from a range of tissue types, in health and disease.

Using adoptive transfer experiments we found that spleen cells from persistently infected (carrier) mice actively suppressed the expected LCMV - specific CTL response of spleen cells from normal adult mice.

In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialized cells, but also maintain the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues.

«Thanks to improvements in the understanding of AML biology, a multiplicity of so - called targeted therapies and therapies based on differential pathophysiology of leukemic stem cells compared with normal counterparts have emerged,» noted Richard M. Stone, MD, clinical director of the Adult Leukemia Program at Dana - Farber Cancer Institute in Boston, and colleagues, writing in a review for the ASCO 2017 Educational Book.

He and his lab study stem cell biology to provide insights into many areas, such as developmental biology, homeostasis in the normal adult and recovery from injury.

Dr Annette Meeson has expertise in the identification and characterisation of adult stem cells, and is involved in optimising isolation techniques for stem cells from both normal, injured and diseased tissue.

Answering this question will require knowledge of whether normal stem cells are susceptible to cancer - causing mutations; however, this has proved difficult to test because the identity of most adult tissue stem cells is not known.

Regenerative medicine aims to use adult or embryonic stem cells to replace or regenerate human cells, tissue, or organs and restore normal function.

Many have used viruses to convert adult cells to stem cells and to carry a normal HBB gene to infect and repair hematopoietic stem cells — stem cells that give rise to all blood cells.

Both adults and children need folate to make normal red blood cells and prevent anemia.

Normal cone cell function can be seen on Electroretinogram (ERG) before six weeks of age, but becomes abnormal between 6 to 12 weeks of age and is completely absent in affected adult dogs signifying complete loss of Cone Cells.

(Type 2 is found more commonly in adult humans and cats, generally arises from obesity, and occurs when the cells of the body become resistant to normal amounts of insulin, as opposed to a lack of insulin production.)