The objective of this project is to discover X-linked loci underlying various age - related complex diseases and
normal aging while putting forth improved statistical genetic methods that are specially designed for ChrX.
Not exact matches
The RSC budget make Social Security sustainably solvent by implementing a slightly modified version of Representative Sam Johnson's (R - TX) «Social Security Reform Act,» which would slow initial benefit growth for higher earners, gradually raise the
normal retirement
age to 70, and eliminate annual cost - of - living adjustments for higher earners
while using the more accurate chained Consumer Price Index (CPI)(currently used for the tax code) for other beneficiaries.
If you wait until your
normal retirement
age to collect benefits, you can claim spousal benefits only on your ex's earnings record
while your own benefits earn delayed - retirement credits.
Her health further declined between the
ages of 21 and 23,
while she struggled to accept the cross of her suffering, «torn between giving all to God and hoping for a
normal life».
Instead, one day a week, we stay in the parents room
while the children are in the classroom, and are led in a discussion on development and
normal behavior of the
age of the class.
While it's
age - appropriate for toddlers to throw temper tantrums, and preschoolers to lash out aggressively at times, it's important to keep an eye out for behavior that goes above and beyond
normal childhood behavior.
The researchers tracked nearly 400 babies at
ages 3, 6, 9, and 12 months, and
while adjusting for socioeconomic status, mother's
age and IQ, gestational
age, gender, birth weight, head circumference, race,
age, and diet history, all soy formula - fed infant scores were within established
normal ranges.
And
while there are
normal developmental milestones that toddlers often reach at relatively similar
ages and stages, all children are different and learn and develop at their own pace.
Positional plagiocephaly, or plagiocephaly without synostosis (PWS), can be associated with supine sleeping position (OR: 2.5).113 It is most likely to result if the infant's head position is not varied when placed for sleep, if the infant spends little or no time in awake, supervised tummy time, and if the infant is not held in the upright position when not sleeping.113, — , 115 Children with developmental delay and / or neurologic injury have increased rates of PWS, although a causal relationship has not been demonstrated.113, 116, — , 119 In healthy
normal children, the incidence of PWS decreases spontaneously from 20 % at 8 months to 3 % at 24 months of
age.114 Although data to make specific recommendations as to how often and how long tummy time should be undertaken are lacking, supervised tummy time
while the infant is awake is recommended on a daily basis.
Stuttering:
While it can cause parents concern, stuttering at this
age is a
normal developmental phase that many children go through.
So this is very developmentally
normal, and
while the sleep going sideways is understandably frustrating, this is also a really, REALLY fun
age.
While some parents might think their baby is sucking on their fingers too much and they may have concerns about whether this might affect their tooth and mouth development, it is actually completely
normal for a baby between the
ages of 2 - 6 months old to want to put things in their mouth.
While it's completely
normal for most kids to start reading around the
age of 6, it's never too early to introduce books to get their excitement roaring.
Our family doc said that it's just
normal at this
age b / c they get easily distracted
while nursing.....
Three groups of middle -
aged mice (about a year old) were studied: one group ate a
normal diet, in which fewer than 30 percent of calories came from fat,
while two others were fed high - calorie diets in which 60 percent of the calories came from fat.
While some narrowing of the spinal canal occurs with
normal aging and does not always cause pain, more severe compression of nerves limits mobility and leads patients to try stronger pain medications and epidural steroid injections in an attempt to control the pain that is associated with walking and standing.
While changes in insulin secretion are unlikely to play a major role in the acute effects of SD, cellular stress in pancreatic tissue suggests that chronic SD may contribute to the loss or dysfunction of endocrine cells, and that these effects may be exacerbated by
normal aging, say the researchers.
While in only the first months after treatment for tumors involving both vocal cords, the youth's voice has returned to near
normal for a young man of his
age.
For example, chronic wounds are the result of insufficient blood vessel formation,
while age - related macular degeneration is the result of abnormal expansion of blood vessels which interfere with
normal processes.
While men experience some decline in the number of sperm, motility, and morphology — the number of
normal sperm — after
age 40, it's generally not enough to prevent them from becoming fathers.
«By being able to distinguish benign from malignant
aging based on distinctive RNA splicing patterns, we can develop therapeutic strategies that selectively target leukemia stem cells
while sparing
normal hematopoietic stem cells,» she said.
While most cases of osteoporosis are caused by
normal aging, another leading cause of the bone - loss disease is a condition called hyperparathyroidism, in which the parathyroid glands release an excessive amount of a hormone that regulates the body's calcium levels.
At the advanced
age of 20 to 22 months (roughly equivalent to 100 years in humans), the Bax - deficient mice still maintained hundreds of follicles
while normal mice had none.
While normal RNA regulation involves regulated and reversible assembly of RNA - protein particles, both increased cellular
age and mutation push the process towards hyperassembly, which leads to altered pools of RNA or RNA regulatory proteins in neurons that contribute to their eventual death.
Mice that had been eating a ketogenic diet performed at least as well on memory tests at old
age as they did at middle
age,
while mice eating the
normal diet showed an expected
age - associated decline.
(21) Moreover,
while the link between excessive visceral adipose tissue and
age - independent diabetes and metabolic syndrome widely known, recent studies suggest instead that it is the accumulation of senescent subcutaneous adipocyte progenitors — and their abnormal metabolic function — that drives similar diabetes - like phenotypes during the «
normal»
aging process.
It should be noted, however, that
while a study on senescent cell ablation in genetically
normal mice would provide at least some evidence on the effect of senescent cells (and their ablation) on promoting cancer, even such a study would likely show less effect than could be anticipated in a large mammal model, since even normally -
aging mice rarely suffer metastatic disease to the extent of
aging humans, as sheer primary tumor volume is generally sufficient to be fatal to mice.
For example, an andropausal man whose serum test results indicate total testosterone at
normal levels may still be experiencing loss of muscle and libido, prostate enlargement, and erectile dysfunction, along with increased risk of cardiovascular disease, osteoporosis and depression, if most of his testosterone is bound, which becomes increasingly likely in men > 50, the
age at which testosterone levels typically begin to decline,
while levels of sex hormone binding globulin (SHBG) increase with
age.14
Most of them are between the
ages of 20 and 60 and they work
normal jobs
while lifting with me just a few times each week.
This creamy formula deeply cleanses and removes makeup with organic neroli and grape seed oils,
while soothing
normal,
aging, or sensitive skin with organic chamomile and calendula.
While many of the symptoms of a low thyroid are written off as
normal for
aging women, it's simply not true.
While aging skin is
normal, especially with more exposure to sunlight, accelerated skin
aging can indicate poor digestive and immune function.
Basic searches allow members to browse by zip code, gender,
age and location,
while advanced searches can include sexual preferences, lifestyle,
normal or naughty photos and relationship status.
Normal searches can be done by location, profile features,
age or gender
while the advanced ones can be done using zodiac sign, religion, children or relationship expectation.
While Ryan has a predilection for dating millennial girls, Sarah is more
normal, clever and of an appropriate
age.
The
Normal School teaches about 550 students between the
ages of 14 and 19,
while also serving as one of 11 teacher practice schools in Finland.
The distinction between difficulty in learning to read and difficulty in learning to write and spell is worth making because there are children who are
normal readers for their
age but poor spellers: these children are dysgraphic (poor at writing and spelling)
while not being dyslexic (poor at reading).
While these findings may seem obvious to anyone who has attended school or parented a school -
age child, they have been accepted as the
normal way that schools do business by parents, voters, and society.
People who work
while receiving Social Security before
normal retirement
age typically will receive a reduction of $ 1 for every $ 2 of income earned above an annual limit ($ 17,040 in 2018).
For example, some couples may decide to claim one spouse's Social Security benefits at
normal retirement
age,
while delaying the other spouse's benefits until
age 70 to allow the second monthly payment to grow.
* The old writeoff times were
age based
while the new ones are duration based but for a student graduating at the
normal age the old times were much longer.
While various conditions and
normal aging of the eye can contribute to these symptoms, it is important that cataracts be ruled out.
If the dog has not had her cycle by 30 months of
age while the chromosomes are
normal, the ovulation can be induced artificially by injecting follicle - stimulating hormone and chorionic gonadotropin.
She may seem like a very different animal
while she is caring for her newborns, but generally she will return to her
normal self after the puppies have reached a certain
age.
While your veterinarian can help you to determine what is
normal for your particular cat's breed and
age, you can also observe your pet's body.
Pets that have behaved a particular way their entire life may suddenly change;
while some afflictions may be part of the
normal aging process and unavoidable, many issues can be diagnosed and treated.
Imagine being a
normal, non-techie user and buying an expensive INR 30,000 smartphone and suddenly after a year, It starts showing signs of
age and
while your iPhone buddies grin wildly at you by upgrading to the latest version of iOS overnight.
Also, internalizing problems, such as separation anxiety, might become more impairing when children have to go to school,
while at younger
ages these problems are seen as developmentally
normal emotions (Gardner and Shaw 2008).
While it's totally
normal for libido to ebb and flow as we
age and cope with a number of stress variables, it's also totally
normal to feel frustrated with...