They found that these mice never developed
normal blood vessels in the intermediate layer, leading to degeneration of the photoreceptors and severe vision impairment.
Cooke said recent lab research suggests that proton pump inhibitors can interfere with
normal blood vessel function — a potential mechanism by which the drugs could affect heart attack risk.
The toxicity of chokeberry extract
on normal blood vessel lining cells was tested and found to have no effects up to the highest levels used (50 ug / ml), suggesting that the cell death effect is happening in a way other than through preventing new blood vessel formation (anti-angiogenesis), a process that is important in cancer cell growth.
«This peptide acts as a «zip code» in that it enables the binding of the nanoparticles only to blood vessels within the tumor and
not normal blood vessels,» says Alnawaz Rehemtulla, a radiologist and environmental health scientist who co-authored the study.
They discovered that the placentas of preeclampsia patients showed more activity in the gene for sFlt1, a protein that blocks the effects of vascular endothelial growth factor and placental growth factor, two key proteins necessary for an adequate placental development and
normal blood vessel health.
Research has shown that either alpha - lipoic acid or acetyl - L - carnitine can help to reduce damage to mitochondria and
improve normal blood vessel tone, allowing blood vessels to relax.
In the EPR effect, abnormal blood vessels that are «leakier» than
normal blood vessels in healthy tissue allow nanoparticles to preferentially concentrate in tumors.