Sentences with phrase «normal bone marrow»

They rapidly become space - occupying and start to crowd out normal bone marrow cells that otherwise would develop into healthy, mature red and white blood cells.

In normal bone marrow, stem cells produce red blood cells that carry oxygen, white blood cells that protect the body from infection, and platelets that are involved in blood clotting.

In humans, a comparison of bone marrow from 14 normal bone marrow donors, 35 multiple myeloma patients and 11 patients with a noncancerous condition called monoclonal gammopathy of undetermined significance (MGUS) showed that Runx2 levels were significantly higher in the multiple myeloma cells.

After 50 days, the skin graft survived only in the five mice given normal bone marrow.

Her goal is to define the molecular architecture and functional significance of a niche, determine how tumor growth impacts the niche, learn how benign and malignant cells compete within a niche, and use this knowledge to design precisely targeted anti-cancer treatments that spare normal bone marrow and improve the efficacy of stem cell - based therapies.

Patients were considered free of MRD if less than one cancer cell could be detected in 1,000 normal bone marrow cells.