Sentences with phrase «normal breast tissue»

Any suspicious area should be checked by one of our doctors to determine if there is a growth, swelling, or just normal breast tissue.

In this study we identify more genes that have specific regulation in normal breast tissue as compared with other organ tissues.»

Your mammogram may show cysts, fibroadenomas, tumors, or other lumps, and these may be made up of normal breast tissue, other kinds of tissue, or a foreign substance.

When viewed with x-rays, a malignancy appears lighter in color than does normal breast tissue.

Plakoglobin is a component of two important structures involved in cell - to - cell adhesion, and the investigators found that suppressing its expression caused CTC clusters to fall apart, reducing their metastatic potential, and also disrupted cell - to - cell contact between breast cancer cells but not normal breast tissue.

«Our findings demonstrate the feasibility of classifying cancerous and normal breast tissues using DESI mass spectrometry imaging,» said Nathalie Agar, PhD, director of the Surgical Molecular Imaging Laboratory, BWH Departments of Neurosurgery and Radiology, senior study author.

We also found that S1P levels are high in breast cancer compared from the surrounding normal breast tissue (Nagahashi M et al, Journal of Surgical Research 2016) that associate with sphingosine kinase 1 activity of human breast cancer (Tsuchida J et al, Journal of Surgical Research 2016).

We previously analyzed the miRNA expression profiles of the cancer cells in the BCSC and NTG cell populations from the 11 surgically resected primary human breast cancer specimens, and the epithelial cells in the stem / progenitor cell and other epithelial cell populations of human normal breast tissue.

Researchers from the U.S. National Cancer Institute have honed in on several genes that have a different physical position inside the nucleus in invasive breast cancer cells than in normal breast tissue cells.

Harvard Stem Cell Institute (HSCI) researchers at Dana - Farber Cancer Institute (DFCI) and collaborators at Brigham and Women's Hospital (BWH) have identified a molecular marker in normal breast tissue that can predict a woman's risk for developing breast cancer, the leading cause of death in women with cancer worldwide.

Their research, published in PLOS ONE, focused on one particular gene — TRIM29 — selected from a pool of 100 genes with regulatory patterns specific to normal breast tissue, to prove the link between breast - specific genes and the pathology of cancer.

But in the same issue of Nature Genetics (vol 9, p 444), Jeffrey Holt and colleagues at Vanderbilt University in Nashville say they have found the gene to be less active in breast tumours than in normal breast tissue.

The key was the development of a special «birdcage» coil for MRI of the mouse mammary glands, and the team began testing a wide range of protocols to get images that could distinguish between cancer, normal breast tissue and fat.

Using cutting - edge techniques enabled by next - generation sequencing, the authors generated complete methylome maps at single nucleotide resolution in a low - passage breast cancer cell line and normal breast tissue (primary human mammary epithelial cells).

But thanks to a new device called MarginProbe ®, which detects electromagnetic differences between breast cancer cells and normal breast tissue, surgeons can now get a more accurate assessment while they operate, sparing many women with early - stage breast cancer from additional surgeries.

(A) MELK expression levels are significantly higher in breast carcinoma (n = 392, red circles) than in normal breast tissues (n = 61, blue circles) in the TCGA breast cancer cohort (Cancer Genome Atlas Network, 2012).

Human subjects: Primary breast cancer specimens and / or normal breast tissue were obtained from patients with informed consent in compliance to Protocol 4344, pre-approved by Stanford Institutional Review Board (IRB).

Our bioinformatics analysis, based on multiple independent large - size cohorts shows that MELK is strongly overexpessed in BBC / TNBC, not only compared to normal breast tissues, but also compared to luminal or ER / PR + breast cancer.

If you're wondering what a cancer lump feels like, know that most of the time lumps are not cancer — in fact, normal breast tissue can feel lumpy too.

Mammary tumor virus sequences have not been detected in normal breast tissue or other tumors.