«Our findings demonstrate the feasibility of classifying cancerous and
normal breast tissues using DESI mass spectrometry imaging,» said Nathalie Agar, PhD, director of the Surgical Molecular Imaging Laboratory, BWH Departments of Neurosurgery and Radiology, senior study author.
Not exact matches
In this particular case, the researchers
used DESI mass spectrometry imaging to look at the distribution and amounts of fatty acid substances, called lipids, within
breast tissue and
normal tissue from 61 samples obtained from 14
breast cancer patients that underwent mastectomy.
The research,
using cells from the
Breast Cancer Now Tissue Bank and due to be published in Nature Communications, also shows that the epigenetic changes are inherited as long as the cell divides, and that the team's manipulations permanently and negatively affected the biology of a normal breast cell from a healthy indiv
Breast Cancer Now
Tissue Bank and due to be published in Nature Communications, also shows that the epigenetic changes are inherited as long as the cell divides, and that the team's manipulations permanently and negatively affected the biology of a
normal breast cell from a healthy indiv
breast cell from a healthy individual.
They compared
normal, non-cancer-forming human
breast tissue cells with cancerous
breast cells
using both of these treatments, contrasting them with cells with unmanipulated mtDNA.
Using cutting - edge techniques enabled by next - generation sequencing, the authors generated complete methylome maps at single nucleotide resolution in a low - passage
breast cancer cell line and
normal breast tissue (primary human mammary epithelial cells).
The most effective
use of natural therapies is to improve cellular function and prevent cancer by promoting the
normal, healthy activity of
breast tissue.