Sentences with phrase «normal cell behavior»

The research suggests that reducing production of the protein, called myoferlin, affects cancer cells in two primary ways: by changing the activation of many genes involved in metastasis in favor of normal cell behavior, and by altering mechanical properties of cancer cells — including their shape and ability to invade — so they are more likely to remain nested together rather than breaking away to travel to other tissues.

Not exact matches

Joe W. Ramos, PhD, deputy director of the UH Cancer Center and collaborators focused on investigating how these oncogenes and related signals lead to dysregulation of normal processes within the cell and activate highly mobile and invasive cancer cell behavior.

At the core of this cell behavior is how the loss of that single gene changes activation levels of dozens of other genes, suppressing genes associated with metastatic disease and increasing activity of genes linked to normal tissue.

On the other hand, when the researchers blocked f - circRNA activity, the cells» normal behaviors were restored.

The new research finds that the stiffness of the extracellular matrix and the availability of certain ligands (molecules that bind to cell membranes) can together determine which genes are actually called on — and whether normal epithelial cells begin to exhibit the behaviors characteristic of highly malignant cancer cells.

While it has been well - established that people should avoid behaviors like smoking to decrease cancer risk, it is less well - known that each time a normal cell divides and copies its DNA to produce two new cells, it makes multiple mistakes.

When an enzyme that normally breaks down 2 - AG was blocked, and the supply of the endocannabinoid was restored to normal levels, these behaviors were reversed, the researchers reported on Nov. 26 in the online edition of the journal Cell Reports.

Only by understanding the behavior of normal cells, she maintained, would scientists learn how to prevent abnormal behaviors, such as cancer.

Still another crucial part of creating a realistic organ proxy is the ability to reproduce a range of physical and other forces that influence normal cell development and behavior in the body.

«We need a range of models to learn about the connections among genes, molecules, cells, synapses and circuits in normal and abnormal cognition and behavior, and to help us understand the risks of particular patients,» says the Broad Institute's Steven Hyman.

Many scientists now believe that — complementing its initial focus on mutated genes — precision oncology must now also address the activity of otherwise normal proteins and molecular pathways that are ultimately responsible for cancer cells» malignant behavior.

His efforts have pioneered the use of the three - dimensional «artificial skin» cultures to study the behavior of both tumor and normal cells that sustain tumor growth, a system known as the tumor microenvironment.

Likely, your immune system aims to remove the cause of abnormal cell behavior, replace these abnormal cells with normal ones and heal your joints.

Possibly a simple oversight made by a world of people who are so captivated by new technologies that they fail to fully consider the consequences, it seems that many consider certain forms of distracted driving, such as the usage of cell phones, to be normal and acceptable behavior.