Sentences with phrase «normal cell structure»

Dr. D'Agostino explains that our normal cell structure are remarkably resilient and are equipped with «metabolic flexibility» — and this is something that can be exploited to our advantage when it comes to defeating cancer.

Not exact matches

Instead, IsoLove re-hydrates tissue to normal, healthy levels, and helps maintain the integrity of the vaginal cell structure and ecosystem.

With this glaucoma type, cells that normally secrete proteins inexplicably start to secrete more and the proteins cluster, forming structures that are too big to pass through the eye's normal fluid outflow pathway.

Matteo Boretto, the first author on this study, commented that «we were very excited to see that we could not only robustly grow and amplify endometrial tissue in a dish, but that the tiny structures were also able to reproduce normal responses of the endometrium to hormones: oestrogen makes the tissue thicken, progesterone then induces maturation including folding (see picture), and subsequent removal of both hormones mimics the cell shedding of the menstrual period.»

Plakoglobin is a component of two important structures involved in cell - to - cell adhesion, and the investigators found that suppressing its expression caused CTC clusters to fall apart, reducing their metastatic potential, and also disrupted cell - to - cell contact between breast cancer cells but not normal breast tissue.

Using normal kidney development as a roadmap, the BWH investigators developed an efficient method to create kidney precursor cells that self assemble into structures which mimic complex structures of the kidney.

This revealed telomeres as dangerous structures during mitosis, because the cells momentarily lost the ability to distinguish between damaged DNA strands and normal telomeres.

I found that culturing cardiac valve cells on synthetic hydrogels preserves their normal properties better than the traditional plastic plates do, and I discovered a signaling pathway connecting the stiffness of the supporting scaffold to the cells» cytoskeletal structure.

«We have converted skin cells to stem cells and developed a highly efficient process to convert these stem cells into kidney structures that resemble those found in a normal human kidney.

When this model was in its softest mode, normal (benign) mammary epithelial cells behaved normally within it, forming cellular structures referred to as acini that capture many key features of the normal in vivo mammary epithelium.

These structures were further examined by tissue - level and immunohistochemical tools, revealing ducts with «excessive layers» of epithelial cells, potentially pre-cancerous lesions that were «highly proliferative» compared to normal ducts, they add.

The team also found that the flightless cormorants have an abnormally high number of genetic mutations affecting cilia — small, hair - like structures that protrude from cells and regulate everything from normal development to reproduction.

He points out that in normal cell division, chromosomes line up near the center of the cell, where a structure called the spindle aligns two copies of each chromosome and helps to separate them.

In addition, the findings may help guide emerging stem cell - directed technologies to generate normal kidney structures for studying and treating human kidney disease.

Electrophysiological recordings of these cells after culture for about 15 weeks revealed proper responses to currents and to inhibition of receptors needed for normal cerebellar signaling, indicating that function had developed along with structure.

Along with restoring structure and function to the p53 mutant protein, this drug compound has the ability to to activate a program that selectively kills cancer cells with this particular mutation while leaving normal cells undisturbed.

Moreover, all of the donated pancreases displayed active insulin - producing beta cells, with some of the cells scattered individually and others clumped with different kinds of hormone - producing cells in the normal pancreatic structures called islets.

Normal anatomical structure and the expression of cell class - specific markers does not demonstrate normal cellular function and connectNormal anatomical structure and the expression of cell class - specific markers does not demonstrate normal cellular function and connectnormal cellular function and connectivity.

Scientists have glimpsed the three - dimensional structure of a protein that protects the ends of human chromosomes, a function that is essential for normal cell division and survival.

In 1963, Hruban and colleagues showed that damaged structures within a cell were sequestered and degraded, and that this was a normal and beneficial response to cellular injuries such as starvation or oxygen deprivation.

By reconstructing the structured order of the living machinery of our tissues, these rejuvenation biotechnologies will restore the normal functioning of the body's cells and essential biomolecules, returning aging tissues to health and bringing back the body's youthful vigor.

These spherical structures are present in normal cells but are disorganised by PML / RARA in leukaemia.

Treating human apoE4 neurons with a structure corrector eliminated the signs of Alzheimer's disease, restored normal function to the cells, and improved cell survival.

We simulate the data with multivariate normal distributions, with two different block structured covariance matrices, which only have covariance for the marker genes in the corresponding cell type.

Vitamin A also balances hormones, encourages normal cell growth and maintains the normal structure and function of skin (and scalp).

These cells are responsible for the normal remodeling of tooth structure.

Linatone Shed Relief also contains choline, important for normal cell membrane structure and function, and vitamins A and E, which are antioxidants and helpful for normal coat and skin health.