«This has implications for potentially reducing
normal cognitive decline with aging, or boosting recovery from brain injury after stroke or traumatic brain injury,» he says.
In 2012, she published the first study to note a faster - than -
normal cognitive decline among people exposed to higher levels of particulates, both those smaller than 2.5 micrometers and even larger ones that are thought to be less harmful.
Not exact matches
Whether any
cognitive decline is the result of pathology or just
normal aging can be determined in two ways, said USC's Han.
As life expectancy has increased, the burden of both
normal age - related
cognitive decline and neurodegenerative diseases such as Alzheimer's has become one of the biggest public health challenges worldwide.
Relentless
cognitive decline as we age is worrisome, and it is widely thought to be an unavoidable negative aspect of
normal aging.
The researchers discovered that mice with genetic mutations that stop this endocannabinoid system from working properly age faster than
normal mice, and show more
cognitive decline.
As adults age, changes in physical health can be a natural part of the process, as can
cognitive decline, which can range from
normal change in cognition to the onset of disorders such as dementia or Alzheimer's disease.
The study subjects underwent a series of
cognitive tests in which both groups scored within the
normal range, indicating that none of the participants were displaying signs of dementia or other forms of
cognitive decline.
I've written about the use of neuropsychological tests for the differential diagnosis of AD, MCI,
normal cognitive aging, and other neurodegenerative diseases, as well as for the prediction of
cognitive decline and conversion from MCI to dementia.
Based upon activity in multiple CNS toxicity assays, we identified an exceptionally potent, orally active, neurotrophic molecule called J147 that facilitates memory in
normal rodents, and prevents the loss of synaptic proteins and
cognitive decline when administered to three - month - old APP / swePS1ΔE9 mice for seven months [7].
The operationalization of mild
cognitive impairment (MCI) led to targeting earlier symptomatic cases of the illness and treatment strategies based less on pathology and more on a chance to halt or slow
decline than there would be earlier in the disease.1 With the development of amyloid imaging, MCI due to AD diagnosis was refined, 2 and early - stage AD was extended further to include preclinical AD, 3 wherein a positive amyloid positron emission tomography (PET) scan or diagnostic low levels of cerebrospinal fluid β - amyloid (Aβ) indicated the presence of pathology in people who were cognitively
normal.
Of course, early
cognitive decline isn't always obvious, and it can be difficult to tell what's really a warning sign of dementia and what is a
normal sign of aging.
Researchers from the Wake Forest School of Medicine found that aerobic exercise appears to boost thinking skills and brain volume in adults diagnosed with mild
cognitive impairment, a condition that sits in between
normal age - related memory
decline and more serious dementia.
«The fact that they can detect this makes you wonder: What about when they get older and they start to have
normal age - related
cognitive decline?
Low B12 levels at any age cause brain shrinkage and
cognitive decline, even within the lower «
normal range,» resulting in inflammation of brain myelin.
«The present findings support recent clinical trials suggesting that regular intake of cocoa flavanols may have a beneficial effect on
cognitive function, and possibly protect against
normal age - related
cognitive decline.»
Normal age - related
cognitive decline means that each of us will, over time: