Sentences with phrase «normal copies of the gene do»
NORMAL / CLEAR - homozygotes with two normal copies of the gene do not develop NAD and can only transmit the normal gene to its offspring.
http://www.optigen.com/ Not exact matches
Both mouse and human males typically die early from the mutation in Mecp2, because their Y chromosome does not supply a normal copy of the gene.
The reason has been a mystery, but some researchers suspect it has to do with one or more of the genes on chromosome 21, which people with Down syndrome have three copies of instead of the normal two.
The Ionis ASO doesn't distinguish between RNA coming from the normal and mutant copy of the gene, so it lowers the amount of both the normal and mutant protein.
Meanwhile, the normal copy of the gene produces a protein that does useful stuff and doesn't cause harm.
In case of SMA, carriers do not show any symptoms of SMA and have one normal copy of SMN1 gene and one mutated, or defective, copy.
CARRIERS - heterozygotes with one copy of the mutation and one copy of the normal gene do not develop NAD but they can transmit the PLA2G6 mutation to progeny.