Sentences with phrase «normal copy of the gene»

After all, tests in many laboratories showed that providing normal copies of the gene should enable patients to make healthy copies of the protein specified by the gene.

As they age, they are at higher risk of developing mutations in the remaining normal copy of the gene.

But oddly enough, the team found that a large percentage of the resulting mice in their study that inherited only normal copies of the gene from their heterozygous parents did in fact have the white spots.

NORMAL / CLEAR - homozygotes with two normal copies of the gene do not develop NAD and can only transmit the normal gene to its offspring.

If you're a carrier of a defective gene for a recessive disorder, that means you have one normal copy of the gene from one of your parents and one defective copy from the other.

Both mouse and human males typically die early from the mutation in Mecp2, because their Y chromosome does not supply a normal copy of the gene.

The findings jibe with previous reports that PCR tests sometimes overlook a gene with large deletions, detecting only the other, normal copy of the gene.

The finding also led them to the protein made by a normal copy of the gene that promotes sleep early in the night and properly regulates sleep cycles.

Researchers used a technique called CRISPR / Cas9 - mediated genome editing, which can precisely remove a mutation in DNA, allowing the body's DNA repair mechanisms to replace it with a normal copy of the gene.

Mice that inherit two normal copies of the gene should not exhibit this coloring.

The researchers bred together mice that each carried one normal copy of the gene and one aberrant copy — that is, they were heterozygous.

Contrary to reports of premature deaths, carriers of the sickle - cell gene were in almost all cases healthy; because genes come in pairs, carriers had one normal copy of the gene, making normal hemoglobin.

If a mutated gene causes damage to or spurs the disappearance of a necessary protein, for example, gene therapy may be able to introduce a normal copy of the gene to restore the function of that protein.

But fish with a normal copy of the gene can't cope when researchers artificially block protein production from the same gene.

About 1 in 25 people in white populations carry one normal copy of the gene and one mutated copy, and 70 per cent of all CF carriers in the northern European group carry the same single mutation in the gene.

... When dopaminergic input comes in, [individuals with the SNPs on one gene copy] would have a chance of having more transmission» than those with two normal copies of the gene.

«Because individuals carrying a single mutant copy of a gene often mate with an individual with two normal copies of gene, defects can be hidden for a generation and then show up in the grandchildren,» Bier adds.

The researchers found that patients from MODY3 families had one of several different mutations in the gene for hepatocyte nuclear factor 1 alpha (HNF -1-alpha) but healthy subjects had normal copies of the gene.

Meanwhile, the normal copy of the gene produces a protein that does useful stuff and doesn't cause harm.

Scientists discovered that when this occurs, a DNA repair process employed within human embryos activates to fix the broken gene, using the normal copy of the gene as a template.

The researchers found that when they performed this procedure, all the cells in corrected embryos wound up containing two normal copies of the gene, Amato said.

Dogs with two normal copies of the gene will not develop this type of cataract.

The dog has 2 normal copies of the gene.

The test identifies dogs that are clear and have two normal copies of the gene, carriers who have one normal copy and one mutated copy, and those who are at much higher risk for developing DM because they have two mutated copies.

The Antagene DNA - based Acral Mutilation Syndrome (AMS) test distinguishes the mutant and the normal copy of the gene and allows separation of dogs into three groups: Normal / Clear (homozygous normal), Carrier (heterozygous) and Affected (homozygous mutated).

If a dog inherits 1 normal copy of the gene and 1 mutant copy, the dog is considered heterozygous for the mutation and is reported as mutant / normal.

This test clearly identifies dogs that are clear (have 2 normal copies of the gene), those who are carriers (have one normal copy of the gene and one mutated copy of the gene), and those who are at much higher risk for developing PRA (have 2 mutated copies of the gene).

The test clearly identifies dogs that are clear (have 2 normal copies of the gene), those who are carriers (have one normal copy of the gene and one mutated copy of the gene), and those who are at much higher risk for developing DM (have 2 mutated copies of the gene).