Sentences with phrase «normal endometrial cells»
Studies demonstrated that Dioxin exposure to normal endometrial cells resulted in a loss of normal progesterone responsiveness (progesterone resistance) which is a striking feature of endometriosis.
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Matteo Boretto, the first author on this study, commented that «we were very excited to see that we could not only robustly grow and amplify endometrial tissue in a dish, but that the tiny structures were also able to reproduce normal responses of the endometrium to hormones: oestrogen makes the tissue thicken, progesterone then induces maturation including folding (see picture), and subsequent removal of both hormones mimics the cell shedding of the menstrual period.»