Sentences with phrase «normal endometrial tissue»

In the 1920s, Johns Hopkins graduate and trained gynecologist John Sampson first coined the term «endometriosis» and proposed the idea that endometriosis resulted when normal endometrial tissue spilled out through the fallopian tubes into the abdominal cavity during menstruation.

This overgrowth is more likely to become cancerous than normal endometrial tissue.

Not exact matches

The researchers found that HAND2 methylation is already increased in premalignant endometrial lesions (cancer - prone, abnormal - looking tissue) compared to normal endometrium, and that a high level of methylation predicted a poor response to progesterone treatment (which stops the growth of some pre-cancerous endometrial lesions).

Matteo Boretto, the first author on this study, commented that «we were very excited to see that we could not only robustly grow and amplify endometrial tissue in a dish, but that the tiny structures were also able to reproduce normal responses of the endometrium to hormones: oestrogen makes the tissue thicken, progesterone then induces maturation including folding (see picture), and subsequent removal of both hormones mimics the cell shedding of the menstrual period.»

Two of those endometrial false lines had been highly prized because they supposedly were drawn from normal tissue, which can be invaluable for studying the earliest steps to malignant transformation — potentially helping prevent cancers.

Unfortunately, the cat probably developed pyometra because of abnormal uterine tissue (cystic endometrial hyperplasia or possibly a tumor) and that means that her chances of having a normal pregnancy in the future will be decreased (Rand, Problem - based Feline Medicine).