Melanin produced by melanocytes, is stored within melanosomes and is transferred to keratinocytes by a process known as cytocrinia (the same process by which melanin is transferred, in
a normal epidermis, from melanocytes to keratocytes).
To further confirm this observation, the intensity of nuclear staining and the percentage of nuclear positive cells obtained from immunohistochemistry analysis of 17
normal epidermis and 34 SCC specimens were analyzed statistically.
Our results revealed that among the DDX3 - positive cells of
normal epidermis, DDX3 was localized mainly in the nuclei and less in the cytoplasm (Fig. 6A).
The green - labelled cells show a basal cell carcinoma in mouse tail epidermis derived from a single mutant stem cell and expanding out of
the normal epidermis stained in red.
Not exact matches
Microscope images show that in
normal skin (left) the top layer, called the
epidermis (purple in bottom images), is fused to the dermis by laminin 332 (green, in top images) and other proteins.
Human
epidermis was shown to persist for at least three months, i.e. three full renewal cycles, displaying
normal human skin characteristics.
This approach reveals that a single population of progenitor cells maintains
normal cell turnover of the
epidermis and oesophageal epithelium.
First described in 1842 by Gustav Simon, a French dermatologist, Demodex mites are
normal skin inhabitants of many mammals, and > 140 species of Demodex have been identified (2 in humans, 3 in dogs).1 The mites live in hair follicles as well as the sebaceous glands and ducts and feed off of sebum, cells, and debris from the
epidermis.2, 3 In dogs, the mites are passed from the bitch to her puppies through close contact while nursing.
After completion of treatment and confirmation of
normal flora by cytology, then apply OticArmor to help patient comfort, shield the
epidermis and aid in lengthening the time between reoccurrence.