Sentences with phrase «normal female mice»

To test a nonpermanent approach, the team gave normal female mice the MIS protein as a twice - daily shot.

DOUBLING UP A normal female mouse embryo (left) has only female reproductive tissue, called the Müllerian duct (pink).

Not exact matches

Human females can live a normal life span with the disease, as can female mice — the latter species also frequently becomes obese.

Male mice from both strains lived 15 per cent longer than normal mice or females.

Older modified male mice metabolised sugar faster than normal mice and females, suggesting that SIRT6 might extend life by protecting against metabolic disorders such as diabetes.

These modified mice had significantly smaller testes and lower sperm counts than their normal counterparts — and when the group bred them with normal females, they found that the litter size was around half normal.

By contrast, these females retained a normal level of social interest in other females during estrus, and in male mice when not in estrus.

To determine what effect this had on fertility, Cook - Andersen's team set up an equal number of fertile male mice with 10 females lacking L2 in their eggs and 10 normal females.

These mice were then mated with females that hadn't been confined, and their resulting offspring had higher blood glucose than normal.

In the latest study, the researchers injected the nine miRNAs into zygotes from normal mice, implanted the zygotes in females, and allowed them to mature.

But when researchers used that sperm to fertilize eggs in the lab that were then injected into female mice, the mice birthed pups at a normal rate.

To investigate, Akhtar deleted the gene for Rac1 in female mice; their first litter of pups survived, but they were smaller than normal — probably because the milk they received contained less fat and protein than normal.

The molecules are critical to normal development: When the genes for certain of these molecules are experimentally erased, the eggs made by female mice are invariably defective, and the errors fatally disrupt the normal choreography of egg maturation.

While these XX male mice had the same level of testosterone as normal XY mice, they displayed more masculine sexual behaviours — mounting females more often and ejaculating more frequently.

When the team genetically engineered female mice to be unable to make these NK cells, the animals had fetuses that were half normal size.

When the treated mice matured, the females gave birth to normal numbers of pups, another sign that the skeleton — specifically, the pelvis — had reached full adult size.

Female mice and male mice that had been treated with estrogen were able to clear the bacteria from their lungs more rapidly than normal male mice.

Thus, mutation of mouse Boule disrupts male reproduction but does not affect normal development, growth or female fertility, suggesting that mammalian Boule is required only for male reproduction, similar to fly boule but different from worm daz - 1.