Dr. Verma's major research interests are oncogenes and tumor suppressors,
normal genes whose alteration can cause cancer, and the development of techniques for gene therapy.
Not exact matches
Using RNA sequencing, the researchers found multiple
genes whose abnormal expression could lead to the high rate of death for cloned embryos, including failure to implant in the uterus and failure to develop a
normal placenta.
Under
normal circumstances, people
whose taste receptor cells make more messenger RNA (mRNA) for a given
gene make more of the encoded receptor.
Patients
whose tumors had a
normal BRAF
gene showed an overall objective response rate of 61 %.
The specific mutations that the researchers observed are «dominant negative» mutations, meaning, when present on even one copy of P53, they are able to compromise the function of the
normal protein,
whose components are made from both
gene copies.
Unlike typical eukaryotic organisms, Tetrahymena has two nuclei — a micronucleus that contains
normal chromosomes and a macronucleus
whose chromosomes are fragmented into thousands of small pieces of DNA that all encode the same ribosomal RNA
gene.
I have seen many patients over the years with Hashimoto's
whose health care practitioners have told them they can eat gluten because they had a
normal gluten antibody test (meaning there is no sensitivity) or they did not have the
gene for gluten sensitivity.
If a dog is diagnosed with a genetic disorder, it can be replaced with a
normal sibling or parent and bred to a mate
whose risk of having liability
genes is low.
The mutations may be in
genes governing some aspect of the immune system but they might also be in tumor suppressor
genes whose job it is to seek out and destroy cancerous cells,
genes that control cell division,
genes that control
normal cell death, and other types as well.
The apparently «
normal footed» cats would have been polydactyls with barely discernible extra toes, but
whose offspring had more prominent extra toes - giving the appearance of either spontaneous mutation or recessive
genes.
Corgi PRA is caused by a mutation in the
gene called PDE6A
whose normal state is essential for
normal vision.
A dog with
normal patellas
whose dam had luxating patellas will likely be carrying a much higher number of the
genes needed to produce luxating patellas than a dog from two
normal parents.