Sentences with phrase «normal genome»

The results followed next generation, whole genome sequencing of the tumor and normal genomes of 16 tumors from 13 rhabdomyosarcoma patients.

Genome pairs consist of a tumor genome with a matched normal, while genome trios consist of two tumor genomes from the same patient along with the matched normal genome for those two tumors.

Data delivered includes the full data set for each genome within the Sample Group as well as results from paired analysis between the tumor and the matched normal genome samples.

The aim of resequencing studies is to determine the candidate pathogenic variants from individual genomes, or from family - based or tumor / normal genome comparisons.

Of 17 retrovirus oncogenes identified to date, 16 are known to have close relatives in the normal genomes of vertebrate species.

But there is no such thing as a normal genome — all of us carry a number of mutated and nonfunctioning genes.

The CSHL Cancer Genomics group seeks to understand how the cancer genome differs from the normal genome, how these differences lead to the growth and development of cancer, and how biomarkers can be used for diagnosis and prognosis.