While testing the effect of many normal, non-cancerous, human cells on the sensitivity of cancer cells to chemotherapy, they found a specific sample of
normal human skin cells that rendered pancreatic cancer cells resistant to gemcitabine.
Not exact matches
Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different
human cell types, including
normal and cancerous colon, lung and liver
cells, as well as brain,
skin, blood and embryonic stem
cells.
A comparison of epidermal equivalents generated from iPSC, hESC and primary
human keratinocytes (
skin cells) from
skin biopsies showed no significant difference in their structural or functional properties compared with the outermost layer of
normal human skin.
«We have converted
skin cells to stem
cells and developed a highly efficient process to convert these stem
cells into kidney structures that resemble those found in a
normal human kidney.
MCC is associated with a virus, the Merkel
cell polyomavirus, which is quite common, often found on
normal human skin and surfaces that are frequently touched, Dr. Nghiem says.
US scientists have successfully generated hypothalamic - like neurons from
human induced pluripotent stem
cells (hiPSCs) taken from the blood and
skin cells of super-obese individuals and people with a
normal body weight.
If they were permanent, ES
cells would never be able to differentiate into heart, kidney, brain, bone,
skin and the other specialize
cells crucial to
normal human functioning.
IgG and IgA with potential microbial - binding activity are expressed by
normal human skin epidermal
cells.
We have developed a sequencing based approach to show similar in
human tissues, finding around a third of
cells in
normal sun exposed facial
skin carry cancer driver gene mutations.
First described in 1842 by Gustav Simon, a French dermatologist, Demodex mites are
normal skin inhabitants of many mammals, and > 140 species of Demodex have been identified (2 in
humans, 3 in dogs).1 The mites live in hair follicles as well as the sebaceous glands and ducts and feed off of sebum,
cells, and debris from the epidermis.2, 3 In dogs, the mites are passed from the bitch to her puppies through close contact while nursing.