They can put pressure on
normal kidney tissue and compromise the filtering ability of the nephron.
That is because it takes time for these fluid - filled cysts to enlarge sufficiently to destroy
the normal kidney tissue around them.
These sacs (cysts) tend to multiply in number and grow in size over time, eventually overwhelming
normal kidney tissue and often leading to potentially fatal kidney failure.
Lead author Christina von Roemeling, a graduate student at Mayo Clinic in Florida, used genomic profiling of nearly 100 kidney cancer patient samples to identify genes that were either over-expressed or under - expressed as compared to patient matched
normal kidney tissue samples.
Because the NPTX2 gene is not expressed in
normal kidney tissue, a drug designed to target its protein would provide a highly focused treatment, Dr. Copland says.
Not exact matches
The researchers examined an equal number of samples (72) of
normal kidney and
kidney cancer
tissues.
When
normal mice were exposed to TNF, all
tissues studied (liver,
kidney, spleen, thymus, colon, and lymph nodes) produced large amounts of A20 and the mice survived unharmed.
Tissue samples were analyzed from the
kidneys of 15 individuals with high blood pressure and also 7 individuals with
normal blood pressure, and their miRNA and mRNA were compared.
* A growing body of research indicates that Grape Seed OPCs may help to support the health of vascular, bone,
kidney, brain and other
tissues by supporting a healthy immune response to
normal oxidative and metabolic stress.
It is the small pink circle of
tissue that lies to the left of the dark brown
kidney, which in this picture is surrounded by
normal fat.
Pathologists that examine
kidney tissue from pets with failing
kidneys have noticed that many have a higher than
normal number of inflammatory cells invading this area.
Clinical and laboratory research has shown that certain herbs can support
normal function of the liver,
kidneys, heart and immune system; reduce inflammation and improve blood flow through damaged
tissues; promote the differentiation, aging and death of tumor cells; and reduce pain.