Sentences with phrase «normal lab mice»

Not exact matches

Lead author David W. Frederick, PhD, a postdoctoral fellow in the Baur lab, and the team generated mice in which they could restrict the amount of NAD in specific tissues in order to simulate this aspect of normal aging in otherwise healthy mice.

Knowing that the SCN cells in their LHX1 - deficient mice were similarly impaired, a graduate student in Blackshaw's lab, Joseph Bedont, reasoned that their mice might now be able to return to normal temperature cycles if given pulses of heat.

He and colleagues at the University of California, San Francisco, injected the brains of mice with prions they had created in the lab by misfolding normal prion protein, known as PrP.

The mouse models of autism on a normal lab diet (with a medium glycemic index) are already known to generate fewer new neurons, and some of their existing cells and neuronal connections are abnormal compared with those of normal mice.

But when researchers used that sperm to fertilize eggs in the lab that were then injected into female mice, the mice birthed pups at a normal rate.

As controls, fibroblasts and secretions from normal lab rats, mice, and another rodent called the spiny mouse were powerless to stop the human cancer cells growing.

«It was incredible to see that in adult mice, who have gone through normal development and aging, simply overexpressing Arc with a virus restored plasticity,» says co-first author Kyle Jenks, a graduate student in Shepherd's lab.

Ward's lab team took skin tissue samples from her well - established psoriasis transgenic mouse model, called the KC - Tie2 mouse, and compared it to skin tissue samples of normal mice.

For the first time, researchers have been able to grow, in a lab, both normal and primary cancerous prostate cells from a patient, and then implant a million of the cancer cells into a mouse to track how the tumor progresses.

Sinclair's lab is now working on developing what he calls a possible «supermouse» with elevated levels of NAMPT to see if it lives longer and is more disease - resistant than normal mice.

Last year, as a first step in defining a «normal» lab mouse microbiome, they analyzed feces from mice from two major vendors.

Tom Bebee PhD, a postdoc in the Carstens lab and Rohacek compared RNA sequences from the cochleae of normal versus Esrp1 knockout mice.

To test the theory, he and his colleagues analyzed bacteria in fecal samples from lab mice kept in normal 12 - hour cycles of light and darkness.

In their study «D - Serine and Serine Racemase are Localized to Neurons in the Adult Mouse and Human Forebrain,» the lab utilized SR deficient (SR - / --RRB- mice, which have < 15 % of normal D - serine levels, to validate and optimize a D - serine immunohistochemical method.

Young said Celltex did a study in which it injected lab mice with 73 times the normal dose of 200 million cells that Celltex gives its clients, and none of the mice died, developed toxic organs or grew tumors.

In addition to the normal tools of the cell biologist's trade, Simona's lab uses intravital imaging to peer into the brains of mice.

«This mouse strain is great model for this research because they are otherwise healthy and normal, including in their vision, so it allows us to conduct studies focused on cell integration,» said the publication's lead author, Jie Zhu, PhD, a postdoctoral researcher who started in Lamba's lab three years ago.

The study came about when a few scientists in a lab that specializes in sex differences noticed that some mice weren't displaying normal pain responses.

The enhanced endurance was seen in lab mice with a normal oxygen supply and those with oxygen restrictions which provided significant evidence that GW501516 targets and enhances skeletal muscle endurance and recovery time to a supraphysiological level.