Sentences with phrase «normal laboratory mice»

Not exact matches

Laboratory mice that have received rapamycin have reduced the age - dependent decline in spontaneous activity, demonstrated more fitness, improved cognition and cardiovascular health, had less cancer and lived substantially longer than mice fed a normal diet.

Aside from a food intake in laboratory mice that's about 40 percent fewer calories than normal, however, it's been found that another way to activate this pathway is with rapamycin, which appears to have a significant impact even when used late in life.

The researchers induced two groups of mice — germ - free (GF) mice, which are raised in a sterile environment, and specific - pathogen - free mice raised under normal laboratory conditions — to develop forms of asthma or ulcerative colitis.

For comparison, bacteria grown in a laboratory on Earth in normal gravity infected another group of mice.

«The mice looked quite normal until we looked at social memory,» said first author Frederick L. Hitti, an MD - PhD student in Dr. Siegelbaum's laboratory, who developed the transgenic mouse.

Dr. Verdin further found that prolonged intake of a high - fat diet, even in normal mice, can itself reduce the activity of the enzyme produced by SIRT3 — an enzyme his laboratory originally discovered.

◊ mouse models for diseases: phenotyping approaches: courses in English, March 14 - 17 in Illkirch - Strasbourg (CFE, PHENOMIN - ICS) ◊ European Advanced School for Mouse Phenogenomics: in English, June 12 - 16 at Liebfrauenberg in Alsace (PHENOMIN) ◊ necropsy, sampling and histology: June 19 - 23 in Toulouse (ENVT, Anexplo) ◊ normal and abnormal embryology of laboratory animals: March 13 - 17 + May 29 to June 3 + Décember 4 - 8 in Toulouse (ENVT, Anemouse models for diseases: phenotyping approaches: courses in English, March 14 - 17 in Illkirch - Strasbourg (CFE, PHENOMIN - ICS) ◊ European Advanced School for Mouse Phenogenomics: in English, June 12 - 16 at Liebfrauenberg in Alsace (PHENOMIN) ◊ necropsy, sampling and histology: June 19 - 23 in Toulouse (ENVT, Anexplo) ◊ normal and abnormal embryology of laboratory animals: March 13 - 17 + May 29 to June 3 + Décember 4 - 8 in Toulouse (ENVT, AneMouse Phenogenomics: in English, June 12 - 16 at Liebfrauenberg in Alsace (PHENOMIN) ◊ necropsy, sampling and histology: June 19 - 23 in Toulouse (ENVT, Anexplo) ◊ normal and abnormal embryology of laboratory animals: March 13 - 17 + May 29 to June 3 + Décember 4 - 8 in Toulouse (ENVT, Anexplo)

In addition, the normal diurnal feeding rhythms present in mice were significantly blunted in the mutant mice: on a standard laboratory 12 - h light: 12 - h dark (12:12 LD) cycle, nocturnal mice typically consume ~ 75 — 80 % of their total daily calories during the dark phase; in contrast, Clock mutant mice consume ~ 50 % (2).