«Under
normal circumstances, myofibroblasts stimulate wound healing, but when
there's an ongoing injury to an organ (e.g., the
liver of a hepatitis C patient, the heart of a patient with high blood pressure, or the kidney of a patient with diabetes) these proteins clog up
normal functioning,» said Humphreys, a Harvard Medical School associate professor at Brigham and Women's Hospital, who leads the Harvard Stem
Cell Institute Kidney Program.
VLEDs are hypothesised to disrupt this flow of lipid between the
liver and pancreas; within days of VLED commencement
there is a rapid fall in IHCL and within weeks, reductions in pancreatic - fat can be detected with a corresponding return in
normal Î ² -
cell function.