Female mice and male mice that had been treated with estrogen were able to clear the bacteria from their lungs more rapidly than
normal male mice.
But in mixed groups of mutated and genetically
normal male mice, there was no social hierarchy.
Not exact matches
Oxytocin receptor in the Hypothalamus is Sufficient to Resue
Normal Thermoregulation Function in
Male Oxytocin Receptor Knockout
Mice.
Both
mouse and human
males typically die early from the mutation in Mecp2, because their Y chromosome does not supply a
normal copy of the gene.
Male mice from both strains lived 15 per cent longer than
normal mice or females.
Older modified
male mice metabolised sugar faster than
normal mice and females, suggesting that SIRT6 might extend life by protecting against metabolic disorders such as diabetes.
But the
males — despite having smaller testes and lower sperm counts than
normal mice — were clearly fertile and produced offspring.
By contrast, these females retained a
normal level of social interest in other females during estrus, and in
male mice when not in estrus.
To determine what effect this had on fertility, Cook - Andersen's team set up an equal number of fertile
male mice with 10 females lacking L2 in their eggs and 10
normal females.
Transgenic
males weighed 10 percent more than
normal males, but Bartfai says that the heft indicates that the transgenic
mice required less energy to maintain their core temperature.
While these XX
male mice had the same level of testosterone as
normal XY
mice, they displayed more masculine sexual behaviours — mounting females more often and ejaculating more frequently.
Thus, mutation of
mouse Boule disrupts
male reproduction but does not affect
normal development, growth or female fertility, suggesting that mammalian Boule is required only for
male reproduction, similar to fly boule but different from worm daz - 1.