Sentences with phrase «normal myeloid»

On average, in comparison with GO, IMGN632 was 70-fold more cytotoxic to AML progenitors and only fivefold more cytotoxic to normal myeloid progenitors.

Unexpectedly, X-ADC treatment was > 40-fold more cytotoxic to the normal myeloid progenitors than IMGN632 (median IC90 values of 45 pM vs 1900 pM, respectively, in matched samples).

Not exact matches

Activation of these receptors led to a «massive mobilisation» of myeloid - derived suppressor cells (MDSCs), which play a crucial role in lowering the immune system response back down to normal levels (European Journal of Immunology, DOI: 10.1002 / eji.201040667).

Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified RNA - based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already experienced a bout with cancer.

When the researchers mimicked a systemic infection in mice, animals deficient in Del - 1 were slower to begin making myeloid cells again compared to those with normal Del - 1 levels.

Recombinant human granulocyte colony - stimulating factor: effects on normal and leukemic myeloid cells.

Myeloid cells are cells that would have become other blood cells (white blood cells other than lymphocytes, red blood cells or platelets) under normal development.

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome Nature, 456 (7218), 66 - 72 DOI: 10.1038 / nature07485

These flavonoids have almost no toxicity to human normal epithelial, peripheral and myeloid cells.

Tumor necrosis factor - alpha inhibits hTERT gene expression in human myeloid normal and leukemic cells