Not exact matches
While changes in insulin secretion are unlikely to play a major role in the acute effects of SD, cellular stress in
pancreatic tissue suggests that chronic SD may contribute to the loss or dysfunction of endocrine cells, and that these effects may be exacerbated by
normal aging, say the researchers.
The 5E5 antibody recognized multiple types of cancer cells, including leukemia, ovarian, breast, and
pancreatic cancer cells, but not
normal tissues.
Using miR - 192 levels in the cells, the investigators were able to differentiate with very high certainty between
normal and chronically inflamed pancreas
tissue as well as between healthy pancreas
tissue and
pancreatic cancer.
To this end, they compared cancer
tissue samples with
normal tissue as well as with chronically inflamed
pancreatic tissue.
Upon orthotopic transplantation into immunodeficient mice, these organoids form
normal pancreatic ducts and acinar
tissue resembling fetal human pancreas without evidence of tumour formation or transformation.
Bottom Line: Bacterial load was significantly higher in
pancreatic tumor samples from patients with
pancreatic ductal adenocarcinoma compared with
pancreatic tissue from
normal individuals, and in studies using mice, eliminating certain «bad» bacteria slowed the growth of
pancreatic cancer, reversed immune suppression, and upregulated the immune checkpoint protein PD1.
Now, because of I124 - chlor's affinity for
pancreatic cancer over
normal tissues, we can use it in place of FDG to get a more accurate map of the whereabouts of cancer cells.»
At the same time, enough
normal - appearing
pancreatic tissue can be removed to bring the pet's insulin production close to
normal.