Sentences with phrase «normal progression of»

Apart from the normal progression of climate modelling to high resolution, better physics, having a smaller scale to give us better insights into all manner of temperature and weather extremes, which is very, very important and is ongoing and needs to be continued.

Diabetics need not accept the normal progression of their illness.

Crawling has also been held up as a prerequisite to the normal progression of other aspects of neuromuscular and neurological development, such as hand - eye coordination and social maturation.

A good childbirth class will cover not only the normal progression of labor and the stages of labor, but also how to cope with each stage and what might be going on emotionally, physically, and mentally.

Not exact matches

Deformational plagiocephaly generally becomes more severe in the first weeks of life, as the infant holds his head in a fixed position (regardless of the cause for the fixed position); then the headshape begins to improve with normal developmental progression involving head control and a full range of neck motion.

Conference notes that this growing phenomenon includes: (i) management - led working practices which have not been workload impact assessed; (ii) coercive practices such as insidious threats to career progression; (iii) the de facto lengthening of the school day through the expectation that teachers will deliver extra lessons outside of the normal timetable; (iv) the loss of lunch breaks for teachers and students alike; (v) the bullying of teachers into running «booster» and revision classes after school, at weekends and during holiday periods and (vi) the consequential compromising of the teacher's work / life balance.

Several variants, such as the HLA B * 5701 allele, have been associated with the pace of HIV disease progression in both controllers and «normals.»

Overweight and obese MGUS patients had a 55 percent and 98 percent higher risk of progression to multiple myeloma, respectively, than normal - weight MGUS patients.

Now a study has found that the gene mutation's toxic effects require higher than normal levels of a protein called suPAR to trigger the onset and progression of the disease.

After the mice received the MIF inhibitor, their blood sugar levels returned to normal, indicating that MIF is also pivotal in the progression of the disease.

His research is based on the concept that normal brain aging and the pathogeneses of sporadic neurological diseases are not a consequence of a few single or «disease - specific «factors alone, rather they are driven by holistic events that include one's individual genetic and epigenetic condition, progression of aging, and lifestyle.

By conducting an RNA - sequencing experiment of 103 matched tumour and normal colon mucosa samples from Danish CRC patients, 90 of which were germline - genotyped, researchers from the collaborative European project SYSCOL show that both inherited and acquired mutations in non-coding regions of the genome also contribute to cancer development and progression (Linda Koch, Nature Reviews Genetics).

Also, the expression of NUDIX in normal and cancer tissues, and how knock - down of these enzymes affected proliferation and cell cycle progression in both cases, were investigated.

Clathrin is Important for Normal Actin Dynamics and Progression of Sla2p - Containing Patches During Endocytosis in Yeast.

Quiescent PSCs in a normal pancreas act as lipid - storing cells with a limited secretome, whereas activated PSCs in the tumor microenvironment produce a vast array of secreted proteins implicated in cancer progression.

As demonstrated by a recent metaanalysis of prospective cohort studies even obese men and women with normal cardiometabolic clustering had a 4-fold higher relative risk of developing T2DM, although this risk was only half of that of metabolically unhealthy obese patients regardless of sex differences in the progression toward T2DM (40).

Gene Expression Differences in Normal Esophageal Mucosa Associated with Regression and Progression of Mild and Moderate Squamous Dysplasia in a High - Risk Chinese Population

«When we manipulated these master regulators, the gene network returned back towards normal, suggesting that we might be able to therapeutically target these regulators to delay or prevent the progression of CAVD.»

To evaluate whether altered expression of the ABL genes is associated with breast cancer progression and metastasis, we examined the expression of ABL1 and ABL2 in normal and invasive breast tumor specimens using published TCGA (The Cancer Genome Atlas) data sets (14 — 16).

By studying these processes, we hope to gain a better understanding of how cells respond to various stresses to ensure the normal development of tissues and uncover novel pathways that could be exploited to prevent disease progression.

Progression from normal epithelium to colorectal cancer requires an accumulation of mutations in particular genes that affect the balance between proliferation and apoptosis.

We're working to understand how aneuploidy impacts cancer progression, in hopes of developing therapies that can specifically eliminate aneuploid cancers while leaving normal cells unharmed.

Finally, we ask whether the mechanical differences between normal and cancer cells can be used as diagnostic or prognostic markers of cancer progression.

To test whether gut bacteria might influence the progression of colon cancer, the researchers housed normal and AIM2 - deficient mice together, to enable the exchange of gut bacteria.

Using human colon cancer cells and primary human fibroblasts isolated from tumors and adjacent normal tissues, Alexandros Glentis and colleagues at the Institut Curie addressed the question of whether the cancer cells or the CAF cells were responsible for the breakdown of the basement membrane that leads to cancer progression.

Haldar identified a drug that inhibits these proteins and returns their activity levels to normal, blocking the harmful changes in cardiac gene expression and halting the progression of heart damage.

We will also determine whether the release of hormones from dense - core vesicles declines during normal aging and during the progression of neurodegenerative diseases, and thus could be a contributing factor to the age - related decline in neuronal function.

Researchers used a lentivirus to infuse a normal copy of the ABCD1 gene into the bone marrow of boys with cerebral adrenoleukodystrophy (ALD), and the corrected protein stopped disease progression.

These patients had a reduction of 56 % in progression to diabetes, irrespective of the way they reverted to normal glucose regulation regardless if it was only temporary.

By inhibiting cartilage damage, dong quai is effective at actually slowing down the progression of the disease, and this could mean that sufferers can maintain normal functioning for longer, without having to deal with the pain that accompanies osteoarthritis.

A progression from the normal and single leg hip thrust; exactly the same position and movement — just place a barbell on the front of the hips and use two legs again.

Some research also suggests that treating someone with Hashimoto's who otherwise has normal blood tests, including a normal TSH level, may help prevent elevation of the TSH level and progression to full hypothyroidism.

Normal western progression with dumbbells or even barbells to an extent, is to progress to a limited number of reps and continually add weight to an exercise.

That's a normal progression and part of a woman's life cycle.

Those researchers concluded that preventative treatment of normal TSH range patients with Hashimoto's disease reduced the various markers of autoimmune thyroiditis, and speculated that such treatment might even be able to stop the progression of Hashimoto's disease, or perhaps even prevent the development of the hypothyroidism.

Interestingly, it's been many years since the March 2001 issue of the same exact journal, Thyroid, published a German study that found that the use of levothyroxine treatment for cases of Hashimoto's autoimmune thyroiditis where TSH had not yet elevated («euthyroid») beyond normal range could reduce the incidence and degree of autoimmune disease progression.

On the other hand, Smith is the same fellow who, fresh out of the Columbia University MFA writing program, penned the mesmerizing best - selling novel, A Simple Plan, a harrowing morality tale of a sort - of - normal, sort - of - understandable progression of evil in which nine people end up getting murdered.

When those discrepancies happen, and they can be due to many insignificant things e.g. the normal progression or «rolling over» of futures contract expiration dates, the spread can deviate from fair value.

Liz will need DNA from affected dogs, clinical report from the veterinarian or neurologist who diagnosed, samples from normal siblings, parents, and grandparents if possible, brief history of clinical signs and disease progression, and necropsy report if available.

The skin lesions have a similar age of onset and clinical progression, but with dermatomyositis, erythematous plaques or vesicles can not be induced in normal skin by applying mild friction.

Most pets who receive physical rehabilitation have less pain, less complications, less side effects (such as progression of arthritis) and return to normal daily functions (such as walking, sitting, etc) more quickly.

Potassium supplementation seems to help delay the progression of renal failure, especially when the values are lower than normal without supplementation.

In young affected dogs retinal structure, rhodopsin expression and photoreceptor activation is normal; disease progression is characterized by regions of initial focal photoreceptor degeneration surrounded by areas of structurally normal retina, which interestingly is very similar to the phenotypes of humans with RHO mutations [24].

In cases of strikes, political manifestations, natural disasters, adverse weather conditions or any other cases of Act of God which might affect the tourist program's normal progression, IN PERU TRAVEL, will not be held responsible for unfulfilled services.

Playing it basically twice back - to - back (once for normal progression and a second time for speed trophies) made me realize how much of the game doesn't really take advantage of Rayman's many abilities unless you try and speedrun it, but even then, I felt like they could have done more.

Completing the game unlocks a new, more challenging difficulty setting — Normal, Hard, Expert, Crazy, Insane, and Godlike — which brings with it more intricate bullet patterns and tougher bosses, but only the best will be able to see through the entirety of that progression.

Frequently you'll find a level's normal progression to be interrupted by a series of music notes to collect for a bonus, or a quick side area to destroy a bunch of enemies with Yoshi or a Star to earn some one - ups.

Normal Mode and Hard Mode are only different in matters of progression.

This year, the progression of extreme heat and drought has occurred far earlier than normal.

We have been busy doing this as normal as part of the ring progression process I've outlined before — so the train has been moving and overall the builds are getting more robust and reliable.