Other researchers have shown that caspase - 2 also contributes to the maintenance of
normal synaptic functions.
A role of glutamine has been defined for
normal synaptic function (J Neurochem 2008) as well as dendritic retrograde signaling (Cereb Cortex 2009c), and a potential target uncovered in Alzheimer's disease (Neurochem Res 2008).
Not exact matches
These genes are believed to be essential for the
normal function of nerve cells, and previous studies have linked these mutations to problems with
synaptic function — how neurons communicate with each other.
Haghighi studies
synaptic growth,
function and plasticity in both
normal and diseased animals, aiming to identify the very earliest malfunctions in
synaptic function.
Our main aim is to study
synaptic function under physiological conditions and to investigate how the factors contributing to
normal signalling are altered in disease, identifying new therapeutic strategies.