Sentences with phrase «normal version of a gene»

The study team injected patients with a vector, a genetically engineered adeno - associated virus, which carried a normal version of a gene called RPE65 that is mutated in one form of LCA.

We found that the bacterium had to have a normal version of the gene for it to be transmitted.

Mutation in a proto - oncogene acts in a dominant fashion and converts the normal version of the gene to an oncogenic form that produces a hyperactive growth - stimulating protein.

Prior to this, it was widely agreed that no Dalmatians existed who carried a normal version of the gene that controlled the production of uric acid.

The king cheetah also had a Taqpep mutation while the spotted cheetah had a normal version of the gene.

Not exact matches

The scientists are also experimenting with gene therapy, using a harmless virus to deliver a normal copy of the normal CIB2 gene to baby mice that have the mutated version.

Even when each parent carried two mutant versions of the gene, 10 percent of the next generation had normal flowers.

After fishing stem cells from each individual's own blood, the researchers inserted a normal version of the ABCD1 gene into some of the cells and transplanted them back into the kids.

In contrast, only 7 % to 15 % of newborns with mutated versions of either gene — or normal copies of both — were afflicted.

The two closely related regulatory genes are active in the normal development of mammals and govern how RNAs produced from the genes are joined to make final versions of the encoded protein, a process called alternative splicing.

Similarly, someone who inherits the version of a particular gene that's associated with obesity will be more likely to wind up fat than someone who inherits a normal version, but that tendency can be affected by environmental factors such as how much fattening food is available.

While normal HD genes include up to 40 copies of the DNA sequence CAG, the mutated version is crammed with many more copies.

The researchers also found that although the normal version of Rho suppressed gene activity in E. coli, many genes were active when the protein was in its prion form.

In oncology terms, this double - hit status is called «loss of heterozygosity,» or LOH, to signify that both versions (one from mom, one from dad) of the normal BRCA gene have been hobbled.

Because the girl inherited a defective version of the gene from each parent, she had no normal copy.

Cook and his colleagues were even able to restore some normal walking ability to stum - mutant flies by adding the mouse version of the stum gene.

A normal version of the FMR1 gene sequence, where the fragile X syndrome can develop, contains 5 - 55 nucleotide (CGG) repeats.

This dog, when mated to a non-merle, will produce an entire litter of normal merles, because it carries two versions of the merle (M) gene and all the puppies will inherit one copy from it, thus making them all (Mm).