Sentences with phrase «normal young mouse»

If an old mouse was p16 - deficient, it regrew pancreatic cells and cured itself like a normal young mouse.

Not exact matches

The team found neonatal mice with the mutations had normal - appearing skin, and the dry itchy skin of dermatitis did not develop until the mice were a few months old, the equivalent of a young adult in human years.
Then, he found that mice lacking Klotho died young, after developing arteriosclerosis and other age - related conditions much earlier than normal (Science, 7 November 1997, p. 1013).
Just 11 weeks after getting a single shot of the gene therapy, 10 young mice lacking the ob / ob gene reached weight, insulin, glucose, and leptin levels comparable to normal mice.
The drug had a potent effect — it prevented FOP extra-skeletal bone formation and also preserved limb motion and normal bone growth in young mice.
It restored normal blood sugar and insulin levels in animals that already had diabetes and prevented or slowed its onset in young mice that had not yet developed the disease.
The mice appear younger and more robust than comparably - aged normal mice, have better muscle tone, and do not develop age - related tumors.
For example, Young's research shows normally monogamous prairie voles do not develop pair bonds with their mates if their mu - opioid system is blocked; other studies have found that mice genetically engineered to have no mu - opioid receptors do not prefer their mothers to other mice the way normal baby mice do.
They found that the samples from the older normal mice had the most diversity of their gut microbes, including Clostridia and Bacteroides bacteria not seen in the younger mice that were still getting their nutrition entirely from mother's milk.
Next, Abadir and colleagues compared the effects of different concentrations of losartan and valsartan on young diabetic and aged mice during the proliferation / remodeling phase of wound healing, which involves the regrowth of normal tissue.
Young said Celltex did a study in which it injected lab mice with 73 times the normal dose of 200 million cells that Celltex gives its clients, and none of the mice died, developed toxic organs or grew tumors.
We will inject these mice with either oxidized proteins, bacterial components, or normal saline in a single injection when they are young.
The present study employed Ighb scid mice reconstituted with normal lymphocytes from young (2 -3-mo-old) and aged (20 -25-mo-old) donors and immunized with a protein conjugate of the hapten (4 - hydroxy -3-nitrophenyl) acetyl (NP) to determine whether the molecular changes in antibody repertoire reflect senescence in the B cells or whether they are mediated by the aging helper T lymphocytes.
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