Sentences with phrase «not affect cell»

For decades, experts thought the alpha particles released by radon didn't affect the cell's cytoplasm.

Not exact matches

Regarding intensity, a study published in PLOS ONE found that workout intensity was not affected for individuals talking on the phone, compared to those not using a cell phone, but when it came to texting, workout intensity was significantly lower.

Juno asserted that the clinical hold on the ROCKET trial did not affect plans for its other CD19 - directed CAR T - cell product candidates, including JCAR017, for which the company has launched two clinical trials now recruiting patients.

At this time, trials and plans for its other CD19 - directed chimeric antigen receptor (CAR) T - cell product candidates, including JCAR017, are not affected.

Also I have suggested that the aims of low - grade occasions in cells do not «trickle up» to include interest in higher - grade bodily occasions, even though the physical results of those aims may well affect the entire body.

First seen as poisons, then as life - forms, then biological chemicals, viruses today are thought of as being in a gray area between living and nonliving: they can not replicate on their own but can do so in truly living cells and can also affect the behavior of their hosts profoundly.

Importantly, HAMLET kills only cancer cells and does not affect healthy cells.

Learn how sickle cell disease can affect your baby, if your baby could develop the condition too, and whether you shouldn't tak...

Power has not been fully restored, affecting Garcia - Arraras» own samples of monoclonal antibody cell lines collected for organ regeneration research.

A growing body of research indicates that the B2M - MHC I complex, which is present in all cells in the body except red blood cells and plasma cells, can act in the brain in ways not obviously related to immunity — guiding brain development, shaping nerve cell communication, and even affecting behavior.

But this process is important because «if the apoptotic cells are not properly cleared... it will affect the cell death activation» in organisms like worms and cause persistent inflammation and autoimmune responses in humans.

«Because BX795 targets a common pathway that many viruses use to replicate inside the cell, it could be a new kind of broad - spectrum antiviral that might be used to treat other viral infections, including HSV - 2, which primarily affects the genitals, and HIV, although we have not yet tested it on viruses other than HSV - 1.»

Everyday influences — the weights Dad lifts to make himself muscle - bound, the diet regimen Mom follows to lose pounds — don't produce stronger or slimmer progeny, because those changes don't affect the germ cells involved in making children.

«To my great surprise, even injecting 10 million activated T cells specific to the P1A antigen did not affect tumor growth in this induced tumor model,» says Van den Eynde.

She says that the mistakes don't affect the conclusion of the paper and claims to have recreated these cells over 200 times.

First seen as poisons, then as life - forms, then biological chemicals, viruses today are thought of as being in a gray area between living and nonliving: they can not replicate on their own but can do so in truly living cells and can also affect the behavior of their hosts profoundly.

Yang said the study not only indicated which genes are affected by traumatic brain injury and linked to serious disease, but also might point to the genes that govern metabolism, cell communication and inflammation — which might make them the best targets for new treatments for brain disorders.

Neurons in the hippocampus — which are affected in Alzheimer's disease, epilepsy, and other illnesses — were strongly activated, but the neurons above them were not affected, the group reports today in Cell.

Although researchers do not yet know the biological significance of these discoveries, they say that fully cataloguing the genome may help them understand how genetic variations affect the risk of contracting diseases such as cancer as well as how humans grow from a single - celled embryo into an adult.

Transcranial magnetic stimulation can stimulate brain cells from outside the head, but is not highly targeted and so affects large areas of the brain at once.

While BPA did not affect the number of eggs retrieved, «it's worrisome that any compound could decrease productivity of the ovarian cells,» said Dr. Fred Licciardi, a specialist in reproductive medicine and surgery at the New York University Fertility Center who was not involved in the study.

(Previously, scientists had used CRISPR / Cas9 to repair mutations that affect smaller numbers of people with Duchenne, and in cell types that weren't necessarily clinically relevant.)

So something affecting the basic function and metabolism of cells is saying, «Don't become pregnant until you have got your insulin resistance under control».

Becoming drug resistant does not appear to affect the ability of the virus to infect cells.

Symptoms typically don't become apparent until over 70 % of the brain's dopamine - producing cells have been affected.

This is important because the proportion in which the de novo mutation is present in a patient, as well as the type of cells in which it occurs, may not only determine the clinical outcome of a disease for the patient, but also affect the risk of the parents having another child with the same disease in future pregnancies.

Increasing levels of PUMA only affected stem - like cells that were starting to spread and not the growth of primary tumors.

Molecular details for how APOE protein, which helps clear cholesterol from the body, affects brain cells are not understood.

The cells in primary tumors are already established and are not affected by the inhibitors.»

But it is not clear which cells are targeted by oxytocin, or how the hormone affects neural circuits.

If a given drug cocktail kills 90 percent of the cancer cells but doesn't affect the remaining 10 percent, the resistant tumor cells can take over and cause the tumor to grow back.

The nanogel didn't adversely affect stem cell growth or function, and the encased stem cells didn't trigger a rejection response.

Evans - Freke also says that animal studies show that normal functioning of PDGF RTK in healthy cells is not affected by the drug.

«Bone cells aren't solely studied in isolation in the lab as both local and systemic factors play an important role in their function, so it's important to unpick the multitude of biological factors that can affect their proliferation,» says Dr Pablo Roman - Garcia, a first author from the Wellcome Trust Sanger Institute.

However, blocking TSP1, 2 and 4 did not affect neuron survival, suggesting that there is some other factor in the UTC cells that promotes cell longevity.

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

The lipid type, ceramide, also has a functional role in various signaling pathways and affects synaptic function, although its primary role is not in the synapse, but providing structure in cell membranes.

The research suggests that reducing production of the protein, called myoferlin, affects cancer cells in two primary ways: by changing the activation of many genes involved in metastasis in favor of normal cell behavior, and by altering mechanical properties of cancer cells — including their shape and ability to invade — so they are more likely to remain nested together rather than breaking away to travel to other tissues.

While researchers at the Georgia Institute of Technology don't have a specific application for the doughnut - shaped droplets yet, they believe the novel structures offer opportunities to study many interesting problems, from looking at the properties of ordered materials within these confined spaces to studying how geometry affects how cells behave.

But the diseases that they wanted to study — including inflammatory bowel disease and spinal muscular atrophy — generally did not affect blood cells.

These cells were not affected in patients with SLE, dermatomyositis, or other type I interferonopathies, however, suggesting that the source of interferon - can vary depending on the autoimmune disease.

Jagged1 plays a key role in a cell signaling pathway involved in many body systems, but it was not previously known to affect Duchenne muscular dystrophy.

It's not feasible to study the effects of cosmic rays on real astronauts, such as those living in the International Space Station, because many variables, including the stress of living on a spaceship, can affect cognition, says Patric Stanton, a cell biologist at New York Medical College in Valhalla.

Molecular analysis showed that heart cells in affected animals were poorly developed and had mitochondrial defects, indicating that Sap130 - Pcdha9 gene interactions play a crucial role not only in heart development but also in regulating metabolic function of the cardiac muscle.

His work suggests that deep - brain stimulation — whether electrical or optical — may be most effective when it targets not the neurons themselves but the connections between cells, thereby affecting the flow of activity between brain regions.

My goal is to understand the genetic programs that allowed cells in multicellular entities to evolve a germ - soma division of reproductive labor in specific environments, not to analyze how our multicellular origin has affected the evolution of our societies.

At Emory, the pause has halted not only the CEIRS project with the lab - attenuated PR8 strain, but also a research grant project headed by Anice Lowen that is looking at how the cell types targeted by two different influenza viruses affect their propensity to exchange genes.

[W] e believe the committee has nevertheless carried out its investigation appropriately and have concluded that the allegations do not affect the committee's findings concerning the STAP cell papers,» Noyori said, adding that the allegations would be investigated separately.

«We now have the first marker for the capacity of brain immune cells to remove toxic materials,» says Haass, «and its increase long before full Alzheimer's dementia shows that there is early neuronal injury that does not yet affect memory, but already triggers a microglia response.»

This is clear from the fact that the third drug in the study, sodium nitroprusside, does not affect endothelial cells, but still produced different effects in the veins of black people and white people.