Sentences with phrase «not cellular studies»

That's because the risk level is set using studies of cancer rates among people exposed to radon — not cellular studies.

Not exact matches

«We don't think the matter is settled,» says one of the signers, cell biologist Richard Luben of the University of California, Riverside, citing the leukemia studies and cellular and animal data.

The authors used a time - lapse video recording coupled to single - cell molecular analyses to study the process step - by - step and found that fate decision is not a unique programmed event, but the result of a very dynamic process composed of spontaneous fluctuation and selective stabilisation of alternative cellular states.

Interestingly, when compared to human cellular models, mouse models of PD did not demonstrate the same toxic cascade, according to the study.

The new study shows that despite these outliers, antibiotics don't promote resistance spread by inducing global changes at the cellular level.

«How male and female sex hormones can affect the immune system is important for understanding the molecular and cellular basis of sex differences in diseases like asthma,» says Nicola Heller, an immunologist at Johns Hopkins University School of Medicine not involved in the study.

«To truly understand how endocrine - disrupting chemicals may be affecting pregnancies, the findings show we need to study not only hormone levels, but hormone activity at the cellular level.»

Their new study points to a biomarker in the cellular machinery that could not only serve as an early warning of colon cancer, but potentially be harnessed to counteract advanced forms of the disease, the second - largest cause of cancer death in the U.S.

«Until now, it often has been a real mystery which antigens T cells are recognizing; there are whole classes of disease where we don't have this information,» said Michael Birnbaum, a graduate student who led the research at the School of Medicine in the laboratory of K. Christopher Garcia, the study's senior author and a professor of molecular and cellular physiology and of structural biology.

«This study shows how our teams are leveraging synthetic biology not only to reprogram microbes to create living cellular devices that can carry out useful functions for medicine and environmental remediation, but to do this in a way that is safe for all,» said Wyss Institute Founding Director Donald Ingber, M.D., Ph.D., who is also the Judah Folkman Professor of Vascular Biology at HMS and the Vascular Biology Program at Boston Children's Hospital, as well as Professor of Bioengineering at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS).

«Until now, it wasn't known how these pathogens decide to remain trapped inside a chamber - like vacuole or to move freely in the cellular fluid,» said microbiologist Leigh Knodler of WSU's Paul G. Allen School for Global Animal Health, who co-led the study with Cammie Lesser of Harvard.

The role and importance of lipids has not been studied thoroughly in living cells, both due to technical limitations and the simple fact that cellular lipids constitute a molecular array of overwhelming complexity.

«Now that powerful gene - editing tools, such as TALENs, are readily available, the next step is to streamline their implementation into stem cell research,» said Dirk Hockemeyer, PhD, assistant professor of molecular and cellular biology at the University of California, Berkeley, who was not involved in this study.

But in a study published April 5 in Cell, Kevan Shokat, PhD, a professor of cellular and molecular pharmacology, and postdoctoral researcher Qi Hu, PhD, discovered that another common cancer - causing mutation in a GTPase called Gαs (or G - alpha - s) subverts the model: it doesn't just jam the switch in the «on» position, but also disconnects the switch entirely.

Meditation may improve cellular health; however, studies have not separated out effects of meditation from vacation - like effects in a residential randomized controlled trial.

The cellular processes that we have identified in this study as being important for the development of stomach cancer provide new targets for therapy that have not been explored before,» Dr. O'Reilly said.

The advent of human - induced pluripotent stem cell (hiPSC) technology has provided a unique opportunity to establish cellular models of disease from individual patients, and to study the effects of the underlying genetic aberrations upon multiple different cell types, many of which would not normally be accessible.

Our finding highlights a key aspect of cellular transplantation not fully addressed in many short or long - term studies of RPE transplantation: the host inflammatory / immune response to the xenograft and its indirect role in the preservation of the retina.

It isn't an acute treatment for symptom relief, but the studies indicate that those who have optimal levels of cellular magnesium have fewer instances of headaches and migraines.

According to this study, which analyzed data from over 5,800 people, exercise is pretty darn good at preventing cellular aging — a type of aging that doesn't necessarily correspond to how many birthday candles are on your cake.

Stress resistance has not been assessed however and so the biological relevance of this finding is currently unknown.32 Several IER trials (75 - 85 % ER on restricted days) in overweight / obese populations have reported reductions in various markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directions

But basically, she's saying that studies have found changes at the cellular level that we might reasonable expect would have some sort of impact on performance — but that hasn't yet translated to any actual performance boost.

The precise enzyme which scientific studies have found to be responsible for hair loss can not function in an alkaline cellular environment.

Studies show that while eggs, processed meat, poultry and fish may accelerate cellular aging, plant - based diets promote telomere protection, something for which drugs can not complete.

The chart below summarizes a study that found there may not be as much to it as we think, other than simply chasing the muscle pump to elicit blood flow response and anabolic triggering, cellular swelling, hypertrophy, etc..

Finally, clinical studies have not yielded consistent evidence for adverse effects of saturated fat on CVD risk factors other than LDL cholesterol, although reduced insulin sensitivity and increased inflammation have been reported in animal and cellular studies.

One study suggested that at higher doses, curcumin was not protective and may contribute to cellular damage.

Although there are studies examining these cellular pathways in certain models of protein catabolism, including trauma (54), sepsis (55), cancer (56), and denervation (57), the level of severe muscle loss in those states is not comparable to studies assessing weight loss or the effects of exercise interventions.

Which infections are associated with Hashimoto's is still an object of study, but we do know that many of the likely pathogens benefit from high gut, serum, or cellular glucose levels and therefore we can suspect that a high carbohydrate diet might promote the disease and a low, but not too low, carbohydrate diet, such as PHD, might be therapeutic.

Our study also suggests that cellular responses to future ocean conditions are not likely to be straightforward, as shifts in calcification may have less to do with calcification - related genes and more to do with intracellular regulatory processes in cells grown under continuous culture for many hundreds of generations.

The study concluded that the risk of a collision when using a cellular telephone was four times higher than the risk when a cellular telephone was not being used