Sentences with phrase «not cytoplasmic»

We also demonstrate that ACTB haploinsufficiency leads to reduced cell proliferation, altered expression of cell - cycle genes, and decreased amounts of nuclear, but not cytoplasmic, β - actin.

The PERY peptide specifically blocked the interaction of p38 and JNK with the importins, restricted their nuclear translocation, and inhibited phosphorylation of their nuclear (but not cytoplasmic) substrates.

Not exact matches

SV = Secretory vesicle; RER = Rough endoplasmic reticulum; BM = Basement membrane; MFG = Milk fat globule; CLD = Cytoplasmic lipid droplet; N = Nucleus; PC = Plasma cell; FDA = Fat - depleted adipocyte; TJ = Tight junction; GJ = Gap junction; D = Desmosome; ME = Myoepithelial cell.

They found that the N - terminal end of the cytoplasmic tail of gp41, measuring 45 amino acid residues, lacked a regular secondary structure and was not associated with the membrane, which wraps around an HIV - 1 viral particle like the leather cover of a baseball.

But it had no effect on cytoplasmic enzymes, suggesting that it might not reach biomolecules within the bacterium.

But there are also variants of Rbfox1 proteins found in the cytoplasm — the portion of the cell outside the nucleus — and the function of those cytoplasmic proteins had not been understood.

For example, embryologist Jacques Cohen, scientific director at the Institute for Reproductive Medicine and Science of Saint Barnabas in Livingston, New Jersey, has developed a procedure called cytoplasmic transfer that shows promise for assisting women approaching their early forties who either can't get pregnant through in vitro fertilization or have embryos of such poor quality they don't survive.

For instance, by ensuring that infected males can't reproduce with uninfected females — a phenomenon called cytoplasmic incompatibility — the bacteria can maximize the number of infected offspring in the next generation and sweep through populations in very little time.

Removing the cytoplasmic domain may distract the immune response and instead generate antibodies that target epitopes on Env that would not lead to protection.

As full length Bk132 Env would not pseudotype on an NL43 HIV core we truncated the cytoplasmic tail of the Envs [49], [50], and conducted tropism testing on NP2 cell lines expressing CD4 with either CCR5 or CXCR4.

Found that proteins bound to the cytoplasmic portion of one subtype of glutamate receptor, the N - methyl - D - aspartate receptor, play a critical role coupling local calcium influx through the channel to elicit adaptive gene transcription in neurons.

Apoptotic actions of p53 require transcriptional activation of PUMA and do not involve a direct mitochondrial / cytoplasmic site of action in postnatal cortical neurons.

However, while heme has been reported to induce nuclear export and subsequent cytoplasmic degradation of Bach1, HPP - 4382 does not appear to alter the steady - state levels or nuclear - cytoplasmic distribution of Bach1 (data not shown), suggesting that HPP - 4382 may not fully mimic the action of heme as a ligand of Bach1.

Our gene expression and embryo development data suggest that FSH and LH may not affect oocyte nuclear and cytoplasmic maturation directly.

Importantly, spreading and migration do not occur with cells expressing NG2 variants lacking the cytoplasmic domain of the proteoglycan, suggesting that interaction of NG2 with cytoplasmic ligands is required for these processes to take place.

Although the cyst structure is not present in mammalian spermatogenesis, descendant cells from a single spermatogonial stem cell remain connected with each other through cytoplasmic bridges during mouse sperm development, similar to that in Drosophila spermatogenesis [62]--[65].

The images clearly show that both lithium (n) and rapamycin (p) change the cytoplasmic diffuse fluorescence pattern of GFP - LC3 to a punctuated pattern indicative of autophagosome formation.