«These are
not dormant cells — they divide once every six or seven weeks as opposed to every other day like the rest of the melanoma cells,» Herlyn explained.
Not exact matches
«Contrary to what was previously thought, children with LCA and defects in RPE65 or LRAT are
not born with dead retinal
cells; the
cells can simply go
dormant, and they can remain
dormant for years before they eventually die.
Specifically, they found that chemotherapy alone leads to two types of
dormant cancer
cells that are
not killed outright and become resistant to additional chemotherapy, but when combined with immunotherapy, a majority of
dormant cells also is destroyed.
Then, they treated the
dormant cells with a product of the immune system, they found that
dormant cells were susceptible to immunotherapy, and that quiescent, but
not indolent cancer
cells, could
not escape from immunotherapy.
They lie
dormant and can
not be eliminated by anti-retroviral therapy, nor by the weakened immune system, so that if treatment is stopped at any time, the virus starts to replicate and infect more
cells again, while the immune system can
not suppress this rebound of HIV infection.
Professor Spano explained: «
Dormant CD4 T
cells infected with HIV are
not actively producing HIV: they are latently infected.
They all sounded three sour notes: that they had cured only about half of their mice; that they did
not know whether the mice had grown new islets or merely revived
dormant ones; and that they had found no evidence that spleen
cells had converted to beta
cells.
It was thought, but until now
not demonstrated, that inhibitors of immune check - points could, in a similar way, wake up
dormant HIV - infected
cells and also the immune defences against the virus.»
Dormant or latent viruses hide in
cells,
not in body fluids such as saliva or nasal secretions, Wylie explained.
Moreover, these compounds kill so - called MRSA «persister»
cells that are drug - resistant
dormant cells that are
not susceptible to current antibiotic therapies.
One hypothesis is that beta
cells in some islets may remain
dormant until needed, and thus
not age as quickly, Bonner - Weir says.