Sentences with phrase «not hematopoietic stem»

Exonuclease 1 is essential for maintaining genomic stability and the proliferative capacity of neural but not hematopoietic stem cells.

Not exact matches

A transplant of hematopoietic stem cells attempts to cure patients with certain cancers and other serious illnesses that have not responded to conventional chemotherapies.

«A hematopoietic stem cell's decision to become a certain cell type can not be observed.

«You don't want to have too many or too few hematopoietic stem cells.»

Basic research has centered on identifying and characterizing hematopoietic stem cells, however, it is still not clear how hematopoietic stem cells actually work, and how they are regulated because of the complexity of the bone marrow microenvironment.

The results make it clear, says stem - cell biologist Amy Wagers, who headed the study, that these hematopoietic stem cells can do a lot for blood diseases but not for diseases affecting other kinds of cells.

Importantly, this genetic alteration did not affect normal hematopoietic (blood) stem cells.

It would have been more appropriate to note that their review targeted hematopoietic stem cell transplantation because embryonic stem cells are not yet ready for clinical use.

Furthermore, stem cells in bone marrow may form not just hematopoietic cells, but cardiac muscle cells, neural cells, and other types of cells; this is an example of stem - cell plasticity.

This new knowledge has paved the way for the therapeutic transfer of stem cells not only for the treatment of hematopoietic diseases by bone marrow transplantation â $» first attempted by E. Donnall Thomas, one of this bookâ $ ™ s editors, in 1957 â $» but also for the treatment of many other disorders.

Scherf N, Franke K, Glauche I, Kurth I, Bornhäuser M, Werner C, Pompe T, Roeder I On the symmetry of siblings: automated single - cell tracking to quantify the behavior of hematopoietic stem cells in a biomimetic setup.

Title: Hematopoietic Stem Cell Function and Survival Depend on c - Myc and N - Myc Activity Authors: Laurenti E, Varnum - Finney B, Wilson A, Ferrero I, Blanco - Bose WE, Ehninger A, Knoepfler PS, Cheng PF, MacDonald HR, Eisenman RN, Bernstein ID, Trumpp A Date: 2008 Publication Details: Cell Stem Cell, Volume 3, Issue 6, 611 - 624, 4 December 2008

Title: On the symmetry of siblings: automated single - cell tracking to quantify the behavior of hematopoietic stem cells in a biomimetic setup Authors: Scherf N, Franke K, Glauche I, Kurth I, Bornhauser M, Werner C, Pompe T, Roeder I Date: 2012 Publication Details: Exp Hematol.

Arndt K, Grinenko T, Mende N, Reichert D, Portz M, Ripich T, Carmeliet P, Corbeil D, Waskow C. CD133 is a modifier of hematopoietic progenitor frequencies but is dispensable for the maintenance of mouse hematopoietic stem cells.

Grinenko T, Arndt K, Portz M, Mende N, Günther M, Cosgun KN, Alexopoulou D, Lakshmanaperumal N, Henry I, Dahl A, Waskow C Clonal expansion capacity defines two consecutive developmental stages of long - term hematopoietic stem cells.

[11] Chang J, Wang Y, Shao L, Laberge RM, Demaria M, Campisi J, Janakiraman K, Sharpless NE, Ding S, Feng W, Luo Y, Wang X, Aykin - Burns N, Krager K, Ponnappan U, Hauer - Jensen M, Meng A, Zhou D. Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.

Role of hematopoietic stem cells in steady state hematopoiesis It is remain not very clear if all blood cell types are developed from one hematopoietic stem cell (HSC) in normal hematopoiesis, because of limitations of conventional transplantation models.

Not to bore you with the science, but it seems our bone marrow produces more hematopoietic stem cells — the ones that lead to white blood cells — during our peak years, though it is important to note that this doesn't protect us from injury or malnutrition, and it doesn't last.