It is possible that the reason the negatively charged micelles were not found to be toxic was that they did
not invade cells to the same extent as the positively charged micelles.
Farzan and his team discovered in their work with monkeys that HIV can't invade cells if those cells» two surface receptors are blocked — like a keyhole jammed with gum.
Not exact matches
The term «in situ» means that the cancerous
cells are contained within the breast's milk ducts and have
not invaded the surrounding tissue.
The new findings also showed that activation of the AIM2 inflammasome by the DNA virus cytomegalovirus does
not involve IRF1, suggesting that the DNA of the
invading microbes is presented to the
cell in different ways.
Cancer Research UK scientists at The University of Manchester found that some melanoma
cells are particularly fast growing, but
not very good at
invading the surrounding tissue, while other melanoma
cells are the opposite — highly invasive but slow - growing.
Without the right receptor, the virus can
not attach tightly enough to
invade the
cell and co-opt it for replication.
With low levels of active p130Cas,
cells don't form lamellipodia and are therefore less able to
invade.
The research suggests that reducing production of the protein, called myoferlin, affects cancer
cells in two primary ways: by changing the activation of many genes involved in metastasis in favor of normal
cell behavior, and by altering mechanical properties of cancer
cells — including their shape and ability to
invade — so they are more likely to remain
nested together rather than breaking away to travel to other tissues.
When alien species
invade and take over communities, they may
not come alone — many plant species are host to a whole suite of microorganisms that
not only live in plant
cells, but also in the soil surrounding the plants» roots.
Results showed that
not only does anti-androgen receptor therapy reduce the ability of androgen - receptor - expressing triple - negative breast cancers to proliferate, migrate and
invade, but for these
cells, androgen receptor seems essential to survival.
«It seems that in cancer
cells, Myc and its partner Miz - 1
invade to gene controller areas where they are
not supposed to go.
The fact that the hemocytes can be seen in their normal positions within the embryo reveals that these
cells do
not have to actively migrate toward the
invading bacteria but rather are able to recognize and bind the bacteria as they are washed over them in the extra-cellular space.
Back then, biologists were struggling to learn how the fierce little warriors of the immune system — the white blood
cells — know to attack
invading pathogens but
not the body itself.
Complement activation products
not only directly help to eliminate
invading pathogens, but also participate in many immunological reactions, including clearance of immune complexes, antibody production, and T -
cell regulation.
Earlier versions of such vaccines largely failed because they targeted single
invading substances that were
not mutated, so T
cells that attack invaders often ignored them, he says.
Cells of plants and animals have evolved over millennia to produce molecules that specifically degrade RNA of viruses that invade cells while not attacking the cell's own
Cells of plants and animals have evolved over millennia to produce molecules that specifically degrade RNA of viruses that
invade cells while not attacking the cell's own
cells while
not attacking the
cell's own mRNA.
Moreover, recent studies show that T. gondii can deliver effector proteins into
cells that it does
not invade [33], [34], and that these proteins can manipulate host
cells without active parasite replication [35].
Harold Varmus: Well the simplistic way to think about that is and I'm
not sure this is the way it will be worked out, is to be able to take just a few
cells from those early lesions and examine them genetically or for other kinds of marks on the DNA that would predict whether or
not this is some - this is a lesion which might or an early stage growth that might never be able to progress, but it is also possible that every early tumor of that kind has some probability of expanding and
invading and growing to become a medical problem, so getting that right will obviously be crucial because it's very difficult to say when you've diagnosed something that is an early stage tumor that it won't progress.
BSI member Professor Michael Dustin, explains, «While an overwhelming T -
cell response might on the face of it sound effective, it brings risks of immunopathology, where an over-active immune system destroys healthy human tissue,
not just the
invading disease - causing pathogen.
In absence of this characteristic
cells are able to grow rapidly and
invade surrounding tissues even though they may be receiving, but
not processing appropriately, external signals to halt growth.
Helper T
cells do
not attack
invading micro-organisms but decide whether it is a threat and whether to stimulate the B
cells to make antibodies.
Probiotics are equipped to communicate with our immune sampling
cells to let them know that they are friend and
not foe (i.e., toxin or
invading pathogen).
The cause of IBD isn't clearly understood but the end result is the lining of the intestine is
invaded by inflammatory
cells.