First, whether or
not irisin will have the same beneficial effects on humans still remains to be seen.
Not exact matches
«Exercise - induced
irisin may
not only act as an endocrine factor capable of promoting the browning of white adipose tissue, but could also regulate bone metabolism by autocrine mechanisms,» said Chen, who also serves as faculty in the Cell, Molecular & Developmental Biology program at the Sackler School of Graduate Biomedical Sciences at Tufts.
Furthermore, the investigators developed a protocol, that does
not rely on antibodies, to precisely measure how much
irisin increases in people after exercise.
Humans are essentially a gene knock - out — they can't produce FNDC5, and therefore they can't produce
irisin.»
«Spiegelman and colleagues have unequivocally shown that the «mythical»
irisin peptide is produced as a result of exercise,» says chemical physiologist John Yates of The Scripps Research Institute, also
not affiliated with the work.
«Exercise - induced hormone
irisin is
not a «myth».»
This possibility is
not exclusive to myostatin, because the cytokine interleukin - 6 (IL - 6) also plays a critical role in exercise - induced muscle hypertrophy, and the secreted hormone
irisin is released in response to exercise and promotes energy expenditure (57).
«Although an association between exercise - induced
irisin and body composition change was found in obese adults, we could
not evaluate their causal relationship in this study.
That an increase in muscle mass is accompanied by an rise in
irisin concentration is
not surprising, but how a decrease in body fat boosts
irisin levels remains a mystery to the Koreans.
This possibility is
not exclusive to myostatin, because the cytokine interleukin - 6 (IL - 6) also plays a critical role in exercise - induced muscle hypertrophy, and the secreted hormone
irisin is released in response to exercise and promotes energy expenditure (57).