Sentences with phrase «not luminal»

Not exact matches

Those clear patterns were not seen in the luminal cancers.

Title: Developmental stage - specific contribution of LGR5 + cells to basal and luminal epithelial lineages in the postnatal mammary gland Authors: de Visser KE, Ciampricotti M, Michalak EM, Wei - Min Tan D, Speksnijder EN, Hau C - S, Clevers H, Barker N, Jonkers J Date: 2012 Publication Details: The Journal of Pathology 2011 May; 224 (1): 56 - 66

In contrast, in five luminal breast cell lines, MELK knockdown with equivalent efficiency did not result in obvious inhibition on cell growth (Figure 5E, Figure 5 — figure supplement 1A, B).

It could be that the degree of knockdown of MELK in the luminal cell lines did not go below a necessary threshold to cause a proliferation effect.

Our bioinformatics analysis, based on multiple independent large - size cohorts shows that MELK is strongly overexpessed in BBC / TNBC, not only compared to normal breast tissues, but also compared to luminal or ER / PR + breast cancer.