Sentences with phrase «novel agents»

The only problem was it wasn't the romance novel the agent envisioned.

His work focuses on the application of medicinal chemistry to the development of novel agents for the treatment of tuberculosis.

As a medical anthropologist, she specializes in the study of multi-disciplinary models for integrative medicine (healing circles) and the emergence of Health Coaches as novel agents in health behavior change.

«Ultimately, in the case of autoimmunity, we should be able to use these techniques as a high - throughput assay to screen hundreds or thousands of compounds that might block the effects of autoantibodies and identify novel agents with therapeutic potential in given individuals,» says Sinha.

Abstract SY28 - 04: Rational incorporation of novel agents into multimodality treatment of glioma and neuroblastoma

When treatment begins to fail, University of Chicago medical oncologists with expertise in GIST can offer treatment with multiple novel agents, including sunitinib or investigational drugs available only through clinical trials.

In our case report, we discuss a patient with BPDCN, her treatment and prognosis; in addition, we highlight the available treatments and the future novel agents coming up for the treatment of BPDCN.

Upcoming interventional trials will examine immunotherapy in combination with other novel agents in an effort to improve both short - and long - term outcomes for patients.

We are also interested in the evaluation of novel agents which inhibit cellular pathways known to be important in myeloma pathogenesis.

Toward this end, the company is leveraging unexploited insights in immunology to discover novel agents that combat cancer by reversing tumor immunosuppression.

«A better understanding of how microtubule dynamic instability is regulated could open new opportunities for improving the potency and selectivity of existing anti-cancer drugs, as well as facilitate the development of novel agents,» Nogales says.

As a medical anthropologist, she specializes in the study of collaborative models for integrative medicine and the emergence of health coaches as novel agents in health behavior change.

Case report: Conjunctival infestation with Thelazia gulosa: a novel agent of human thelaziasis in the United States.

PHAC and InDRE have teleconference and conclude it may be a novel agent, unrelated to influenza17 April Mexican focal point asks local officials in Mexico to verify news reports of a cluster of cases of acute respiratory illness in Oaxaca hospital.

«The knowledge of the structure of the protein, along with its molecular binding partners, will enable us to greatly advance the understanding of how a-Klotho works and also how to best design therapeutic strategies and novel agents that can either activate or block FGF23 - a-Klotho interaction and signaling as needed.»

A collaborative team of researchers led by Alex A. Adjei, MD, PhD, FACP, of Roswell Park Cancer Institute (RPCI) will share results from the first clinical study of the anticancer effects of the novel agent entolimod at the American Society of Clinical Oncology (ASCO) 51st Annual Meeting in Chicago.

«Our goal is to test this novel agent in patients in order to establish safety and then to proceed quickly to rapid clinical development.

We need novel concepts, novel agents that can save lives in those cases, especially for African - American women, whose death rate is twice that of Caucasians.

Opioids and nonsteroidal anti-inflammatory drugs, such as aspirin and ibuprofen, «have been used in one form or another for hundreds of years and still we have not come up with new and novel agents,» explains Sean Mackey, a neurologist and pain specialist at Stanford.

«There are currently no drug therapies available that improve the very limited natural recovery from spinal cord injuries that patients experience,» said Lyn Jakeman, Ph.D., a program director at the NIH's National Institute of Neurological Disorders and Stroke, Bethesda, MD. «This is a great step towards identifying a novel agent for helping people recover.»

In synopsis, the characterization of the kinetic parameters of BuChE and BNC, described herein, is both aiding in the design of novel agents and optimizing their translation toward clinical use.

Finally, the researchers also examined whether a targeted genetic screening strategy could identify patients with lesions that could be treated with novel agents.

Ewing sarcoma, Neuroblastoma, Novel agents, Other pediatric solid tumors, Phase 1 clinical trials

Co-investigator Bob Carter, MD, PhD, chief of the Division of Neurosurgery at UC San Diego Medical Center and Moores Cancer Center, noted that this novel agent is the culmination of years of multi-disciplinary efforts.

Research in the Leukemia Program spans from direction of clinical trials to basic molecular studies of leukemia biology, immunotherapy and development of novel agents, and to mitigating the late effects of treatment in long - term survivors.

However, for the majority targeted therapies in development — and their combinations with current standard therapies — there are still no approved diagnostic tools to determine which patients are most likely to benefit from or be resistant to these novel agents or drug combinations.

LSU Health Cardiovascular Center of Excellence received a grant award from the National Heart, Lung and Blood Institute to research the development, a novel agent, MSI - 1346, for therapeutic stimulation of heart regeneration following acute myocardial infarction and heart failure.

The research approaches primarily investigate signaling pathways as potential therapeutic targets in tumor cells and the development of novel agents, either alone or in rationally designed combinations.

These data support further exploration for developing SFN [sulforaphane] as a novel agent to treat depression and anxiety disorders.

Though, I suppose «crappy» isn't the best description for novels agents are rejecting.