Sentences with phrase «novel approaches»

In this case it will yield novel approaches to treating and preventing malaria.

A) To enable protein structure elucidation of membrane proteins the primary target of most therapeutics and large macromolecular complexes such as viruses; B) Design proteins with novel structure and / or function to explore novel approaches to protein therapeutics and deepen our understanding of protein folding pathways.

Underpinning research: Novel approaches to (re --RRB- emerging disease detection and outbreak response using the COMPARE analytical framework WP leader: Ron Fouchier, EMC (2) [email protected] co-leader: Mark Woolhouse, UEDIN (11) [email protected] Objectives: 1.

My interests lie in leveraging the information hidden in large - scale omics data for better understanding of the mutational processes causing human cancer, for identifying potential cancer prevention strategies, and for developing novel approaches for targeted cancer treatment.

Novel approaches for enhanced wound healing include the application of immunosuppressive and pro-angiogenic mesenchymal stem cells derived from adipose tissue (ASCs) alongside a biomaterial carrier [2, 3].

The Lung Cancer Moon Shot is aimed at ending lung cancer using novel approaches on the following fronts:

B) Design proteins with novel structure and / or function to explore novel approaches to protein therapeutics and deepen our understanding of protein folding pathways.

Novel approaches will help industrialize cell therapy development.

However, because it can increase the risk of hypoglycemia, novel approaches for curtailing the risk of low blood sugar are highly warranted,» said Dr. Filip Knop, Director of the Center for Diabetes Research at Gentofte Hospital.

Motivation: The size and complexity of modern large - scale genome variation studies demand novel approaches for exploring and sharing the data.

Ward et al. highlight results from molecular and preclinical studies, discuss clinical trial results to date, describe ongoing investigations, and assess novel approaches for the enhancement of MSC based cardiac regeneration, such as genetic modification.

Dr. Venter has developed novel approaches in genome sequencing.

The center will also pursue novel approaches to identify biomarkers for latently infected reservoir cells.

Dr. Gan and her team discovered new cellular mechanisms that could lead to novel approaches to remove toxic proteins from aging neurons.

The center will also pursue novel approaches to identify biomarkers for latently - infected reservoir cells.

It is vital that novel approaches to respiratory critical care should be considered and funded for future research in the field.

• Novel approaches to maintaining upper airway patency and promoting weight reduction in obstructive sleep apnoea.

Currently, HIPO also explores the integration of novel approaches with potentially high relevance in personalized oncology such as liquid biopsies and immunoprofiling.

She is also interested in developing novel approaches for sharing genetic information within families while respecting individual privacy.

The proposed study aims to investigate two novel approaches for promoting long distance (ie, eye to brain) optic nerve regeneration.

It is anticipated that new findings will help uncover mechanisms underlying human skeletal diseases, including osteoporosis, and will help develop novel approaches to prevent and treat these diseases.

To define the relationship between neuropeptide signaling and aging, we are developing novel approaches for cell - type - specific analysis of neuropeptide signaling in the worm and the mouse.

University of California - Los Angeles Application of novel approaches towards germline toxicity assessment

To enhance communication among program members and disseminate new data and novel approaches

Since nematodes are the only known organisms to use ascarosides, «we don't have to be afraid of interfering with similar biochemistry in animals, plants or humans,» Schroeder said, as researchers seek to identify species - specific ascaroside molecules that may enable novel approaches to deter or disrupt the survival or reproduction of parasitic worms.

For the main conference on September 25 and 26, the event will be structured around 3 plenary sessions, introduced by keynote speakers: Session 1: The Funder, Developer and Regulator as Partners in Innovation Session 2: Novel approaches in clinical development Session 3: Developing more predictive preclinical tools to better reach proof of concept

The focus of my laboratory is on exploring novel approaches for solving the fundamental problem of the failure of CNS projection neurons to regenerate injured axons and developing translational approaches for treating optic neuropathies (e.g., glaucoma) and other types of CNS injuries.

The Leibniz Institute for Zoo and Wildlife Research (IZW) is an interdisciplinary research institute dedicated to developing the scientific basis for novel approaches to wildlife conservation.

«These novel approaches have demonstrated compelling efficacy in pre-clinical disease models, which we hope will translate into benefit for patients.»

His lab develops isogenic human pluripotent stem cells and transgenic animals to model disease, with the goal of delineating novel approaches to influence outcomes for Huntington disease (HD) and Fragile X Syndrome (FXS), the most common genetic causes of dementia and intellectual disability, respectively.

These powerful tools are rapidly changing the way researchers do their work, and providing new and novel approaches to treatments for human disease.

The multidisciplinary studies aim to develop novel approaches to enhance immune function and control / eradicate HIV.

Their ultimate goal is to formulate novel approaches for the development of photo - catalysts and solar cell materials and devices.

It's possible that this new - found knowledge could be used to develop novel approaches to prevent salmonella and other infections triggered by the type III secretion system, including black plague and certain pneumonia types, said Knodler.

He continues to lead an active program of phase I - III clinical trials investigating novel approaches to hematologic malignancies and blood and marrow transplantation.

July 18, 2016 International team describes step - by - step progress in battling toxoplasmosis In the July 14 edition of Scientific Reports (Nature), 39 researchers from 14 leading institutions in the United States, United Kingdom and France suggest novel approaches that could hasten the development of better medications for people suffering from toxoplasmosis.

Thus a combination of larger studies and novel approaches such as GWAS will be needed to accomplish this important task.

More recently, he has focused on triple - negative breast cancer, the role of micro-RNAs in cancer growth and metastasis, tumor heterogeneity and novel approaches to targeting therapy - resistant breast cancers.

Studies in organisms such as mice, meanwhile, can be used to examine more complex functions or perfect novel approaches for use in humans.

Failure to respond to this therapy is in fact a major unmet clinical need of solid tumors and this study may help stratify patients and inform novel approaches to improve clinical outcomes.

Our work incorporates expertise and results from different scientific disciplines and integrates theoretical and applied as well as mechanism - and function - oriented research to develop the scientific basis for novel approaches to conservation of wildlife.

For the published program announcements, see the May 9, 2016 Guide announcements, Novel Approaches to Understanding, Preventing, and Treating Lyme Disease and Tickborne Coinfections (R01) and Novel Approaches to Understanding, Preventing, and Treating Lyme Disease and Tickborne Coinfections (R21).

His insights into this process have suggested several novel approaches to therapy.

At Janelia, the FlyEM Project is developing technology that will enable us to create a map of every neuron and synapse in the Drosophila nervous system, using novel approaches to electron microscopy (EM) as the foundation.

Dr. Parsons had a unique talent to link novel approaches in analytical chemistry with sophisticated techniques in behavioral pharmacology and neurocircuitry, and this approach opens the door to novel, out - of - the - box studies of brain mapping that are recognized as the key to new advances in our understanding of the circuitry of the brain, a major new initiative of the National Institutes of Health.

Our teams develop novel approaches as well as utilize routine routes to synthesize molecular, nanostructured, and solid - state systems; analyze the samples with multiple instruments; and model the results for detailed insight and to predict new systems for synthesis and analysis.

Novel approaches combining observational datasets with models to improve constraints were particularly well represented....

His key investments in regenerative medicine technologies have laid the groundwork for novel approaches to treatments aimed at generating not merely palliative but actual curative and restorative therapies.

OMC also aims at potentiating the existing Conditional Mutagenesis Facility by implementing novel approaches to attain tissue -, stage - and site - specific transgene expression in mouse mutant strains, mainly through lentiviral vector - mediated transduction of blastocysts.

Novel approaches to block its detrimental activities hold great promise for the treatment of multiple sclerosis, spinal cord injury, stroke and traumatic brain injury.