Sentences with phrase «novel class of compounds»

Not exact matches

«Our computer aided drug screening process has now identified two new classes of anti-cancer agents, specifically targeting two distinct and novel mechanisms underpinning cancer,» said Dr Andrea Brancale from Cardiff University's School of Pharmacy, who led on the compound's design.

We developed several computational and machine learning methods to successfully identify behavioral patterns or signatures associated with different classes of reference drugs, from which to predict the class of novel compounds (Brunner et al., 2012, Alexandrov et al., 2015), and more recently developed methods to allow us to compare animal models of AD and its progression, and to identify (in silico) novel compounds from our existing database of thousands of novel and reference compounds with the potential to reverse the AD model behavioral profile.